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成人B族链球菌感染,不包括生殖器感染

[Group B streptococcal infections in adults, excluding genital infections].

作者信息

Peirotti M G, Gonzalez S E, Littvik A M, Vacaflor L, Kassar M A, Moreno S, Bottiglieri M T

机构信息

Hospital Rawson, Bajada Pucará S/N, Córdoba, Argentina.

出版信息

Rev Argent Microbiol. 2002 Oct-Dec;34(4):226-9.

Abstract

Group B streptococcus (GBS) or Streptococcus agalactiae is recognized as a mayor cause of neonatal meningitis, sepsis and infections during pregnancy. However, in recent years there have been several reports concerning GBS infections in non pregnant adult population, specially in immunocompromised hosts and in patients with severe underlying diseases such as diabetes mellitus and cancer. We report a series of 45 cases which occurred in nonpregnant adult population during a period of two years. The average age was 50.8 years and most patients (38/44) had one or more risk factors: diabetes mellitus was the most significant underlying disease. The most frequent infection localization was skin and soft tissues followed by urinary tract infection. Several isolated cases of pneumonia, bacteremia, endocarditis, endometritis and peritonitis were observed. GBS infections should no longer be exclusively considered as perinatal and peripartum events. New clinical presentations are arising in non pregnant adult population with special incidence in immunocompromised hosts. We are obliged to keep this in mind and remember that SGB may be a possible etiologic agent for infections, particularly in skin and soft tissues of diabetic patients.

摘要

B族链球菌(GBS)或无乳链球菌被认为是新生儿脑膜炎、败血症及孕期感染的主要病因。然而,近年来有几篇关于非妊娠成年人群GBS感染的报道,特别是在免疫功能低下的宿主以及患有严重基础疾病(如糖尿病和癌症)的患者中。我们报告了两年来在非妊娠成年人群中发生的一系列45例病例。平均年龄为50.8岁,大多数患者(38/44)有一个或多个危险因素:糖尿病是最主要的基础疾病。最常见的感染部位是皮肤和软组织,其次是尿路感染。还观察到几例孤立的肺炎、菌血症、心内膜炎、子宫内膜炎和腹膜炎病例。GBS感染不应再仅仅被视为围产期和分娩期事件。在非妊娠成年人群中出现了新的临床表现,在免疫功能低下的宿主中发病率尤其高。我们必须牢记这一点,并记住GBS可能是感染的一个潜在病因,特别是在糖尿病患者的皮肤和软组织感染中。

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