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国家治疗结果研究(NTORS):4至5年的随访结果。

The National Treatment Outcome Research Study (NTORS): 4-5 year follow-up results.

作者信息

Gossop Michael, Marsden John, Stewart Duncan, Kidd Tara

机构信息

National Addiction Centre, The Maudsley/Institute of Psychiatry, London, UK.

出版信息

Addiction. 2003 Mar;98(3):291-303. doi: 10.1046/j.1360-0443.2003.00296.x.

Abstract

AIMS

The National Treatment Outcome Research Study (NTORS) is the first prospective national study of treatment outcome among drug misusers in the United Kingdom. NTORS investigates outcomes for drug misusers treated in existing services in residential and community settings.

DESIGN, SETTING AND PARTICIPANTS: The study used a longitudinal, prospective cohort design. Data were collected by structured interviews at intake to treatment, 1 year, 2 years and at 4-5 years. The sample comprised 418 patients from 54 agencies and four treatment modalities.

MEASUREMENTS

Measures were taken of illicit drug use, injecting and sharing injecting equipment, alcohol use, psychological health and crime.

FINDINGS

Rates of abstinence from illicit drugs increased after treatment among patients from both residential and community (methadone) programmes. Reductions were found for frequency of use of heroin, non-prescribed methadone, benzodiazepines, injecting and sharing of injecting equipment. For most variables, reductions were evident at 1 year with outcomes remaining at about the 1 year level or with further reductions. Crack cocaine and alcohol outcomes at 4-5 years were not significantly different from intake.

CONCLUSIONS

Substantial reductions across a range of problem behaviours were found 4-5 years after patients were admitted to national treatment programmes delivered under day-to-day conditions. The less satisfactory outcomes for heavy drinking and use of crack cocaine suggest the need for services to be modified to tackle these problems more effectively. Despite differences between the United Kingdom and the United States in patient populations and in treatment programmes, there are many similarities between the two countries in outcomes from large-scale, multi-site studies.

摘要

目的

英国全国治疗结果研究(NTORS)是该国第一项针对吸毒者治疗结果的前瞻性全国性研究。NTORS调查了在住宿和社区环境中现有服务机构接受治疗的吸毒者的治疗结果。

设计、地点和参与者:该研究采用纵向前瞻性队列设计。在治疗开始时、1年、2年以及4至5年时通过结构化访谈收集数据。样本包括来自54个机构的418名患者以及四种治疗方式。

测量

对非法药物使用、注射和共用注射设备、酒精使用、心理健康和犯罪情况进行了测量。

研究结果

住宿治疗项目和社区(美沙酮)项目的患者在接受治疗后,非法药物戒断率均有所上升。海洛因、非处方美沙酮、苯二氮卓类药物的使用频率、注射及共用注射设备的情况均有所减少。对于大多数变量,在1年时减少情况明显,结果保持在约1年的水平或进一步减少。4至5年时,快克可卡因和酒精使用情况与治疗开始时相比无显著差异。

结论

在患者进入日常条件下实施的全国治疗项目4至5年后,一系列问题行为有显著减少。大量饮酒和使用快克可卡因的治疗效果不太理想,这表明需要改进服务以更有效地解决这些问题。尽管英国和美国在患者群体和治疗项目方面存在差异,但两国在大规模、多地点研究的结果方面有许多相似之处。

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