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自生训练对原发性头痛患者药物使用量的影响:一项为期8个月的随访研究。

Effect of autogenic training on drug consumption in patients with primary headache: an 8-month follow-up study.

作者信息

Zsombok Terezia, Juhasz Gabriella, Budavari Agota, Vitrai Jozsef, Bagdy Gyorgy

机构信息

Laboratory of Neurochemistry and Experimental Medicine, and the Department of Vascular Neurology, Semmelweis University National Institute of Psychiatry and Neurology, Budapest, Hungary.

出版信息

Headache. 2003 Mar;43(3):251-7. doi: 10.1046/j.1526-4610.2003.03049.x.

Abstract

OBJECTIVE

To examine the effects of Schultz-type autogenic training on headache-related drug consumption and headache frequency in patients with migraine, tension-type, or mixed (migraine plus tension-type) headache over an 8-month period.

BACKGROUND

Behavioral treatments often are used alone or adjunctively for different types of headache. There are, however, only a few studies that have compared the efficacy and durability of the same treatment in different types of primary headache, and the effects of treatment on headache-related drug consumption rarely have been assessed even in these studies.

METHODS

Twenty-five women with primary headache (11 with mixed headache, 8 with migraine, and 6 with tension-type headache) were evaluated via an open-label, self-controlled, 8-month, follow-up study design. After an initial 4 months of observation, patients began learning Schultz-type autogenic training as modified for patients with headache. They practiced autogenic training on a regular basis for 4 months. Based on data from headache diaries and daily medication records, headache frequencies and the amounts of analgesics, "migraine-specific" drugs (ergots and triptans), and anxiolytics taken by the patients were compared in the three subgroups over the 8-month period. Results.-From the first month of implementation of autogenic training, headache frequencies were significantly reduced in patients with tension-type and mixed headache. Significant reduction in frequency was achieved in patients with migraine only from the third month of autogenic training. Decreases in headache frequencies were accompanied by decreases in consumption of migraine drugs and analgesics resulting in significant correlations among these parameters. Reduction in consumption of anxiolytic drugs was more rapid and robust in patients with tension-type headache compared to patients with migraine, and this outcome failed to show any correlation with change in headache frequency.

CONCLUSION

Schultz-type autogenic training is an effective therapeutic approach that may lead to a reduction in both headache frequency and the use of headache medication.

摘要

目的

在8个月的时间里,研究舒尔茨式自生训练对偏头痛、紧张型头痛或混合型(偏头痛加紧张型)头痛患者的头痛相关药物消耗和头痛频率的影响。

背景

行为疗法经常单独或作为辅助手段用于不同类型的头痛。然而,仅有少数研究比较了同一疗法在不同类型原发性头痛中的疗效和持久性,而且即使在这些研究中,也很少评估治疗对头痛相关药物消耗的影响。

方法

通过开放标签、自身对照、为期8个月的随访研究设计,对25名原发性头痛女性患者(11名混合型头痛、8名偏头痛、6名紧张型头痛)进行评估。在最初4个月的观察期后,患者开始学习针对头痛患者改良的舒尔茨式自生训练。他们定期进行自生训练,为期4个月。根据头痛日记和每日用药记录的数据,比较了8个月期间三个亚组患者的头痛频率以及患者服用的镇痛药、“偏头痛特异性”药物(麦角类和曲坦类)和抗焦虑药的用量。结果:从自生训练实施的第一个月起,紧张型和混合型头痛患者的头痛频率显著降低。仅偏头痛患者从自生训练的第三个月起头痛频率才显著降低。头痛频率的降低伴随着偏头痛药物和镇痛药消耗的减少,这些参数之间存在显著相关性。与偏头痛患者相比,紧张型头痛患者抗焦虑药消耗的减少更为迅速和显著,且这一结果与头痛频率的变化无任何相关性。

结论

舒尔茨式自生训练是一种有效的治疗方法,可能会降低头痛频率并减少头痛药物的使用。

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