Chen Han-Jung, Liang Cheng-Loong, Lu Kang, Lui Chun-Chung
Department of Neurosurgery, Chang Gung University and Medical Center, Kaohsiung, Taiwan.
Am J Forensic Med Pathol. 2003 Mar;24(1):32-4. doi: 10.1097/01.PAF.0000051521.92605.08.
Amphetamine is one of the most common illicitly abused drugs in certain countries. It is a potent sympathomimetic that may lead to vascular events, including stroke and myocardial infarction. Most reports of stroke after amphetamine abuse are of intracerebral hemorrhage. In this report, the authors describe a ruptured aneurysm of the right internal carotid artery in a young man with amphetamine abuse. It grew rapidly within 2 weeks. Surgery revealed fibrosis and fibrinoid necrosis around the aneurysm. The aneurysm was successfully embolized with Guglielmi detachable coil. A rapidly growing aneurysm in the major intracranial vessels resulting from amphetamine abuse is very rare.