Shida Kenji, Yasumoto Kazumasa, Yokoyama Toshirou, Maeda Takeshi, Ohtsuka Naoki, Hosoyamada Akiyoshi
Department of Anesthesiology, Showa University School of Medicine, Tokyo 142-8666.
Masui. 2002 Dec;51(12):1368-70.
Hydrogen peroxide is widely used for irrigation of surgical wounds. However, its administration has been associated with gas embolism. We report a case of gas embolism after wound irrigation with hydrogen peroxide in a 11-year-old boy undergoing extraction of the extra-traumatic splint under general anesthesia. When 3% hydrogen peroxide 12 ml was applied to wound of the left femur after extraction of the splint, the patient showed clinical signs of pulmonary embolism. Symptomatic treatment was initiated immediately. When the patient awoke from anesthesia, he showed tonic convulsion. But he recovered without any complications. The administration of hydrogen peroxide into a closed tissue is contraindicated during surgery.
过氧化氢广泛用于外科伤口冲洗。然而,其应用与气体栓塞有关。我们报告一例11岁男孩在全身麻醉下取出创伤外夹板后,用过氧化氢冲洗伤口后发生气体栓塞的病例。在取出夹板后,当向左侧股骨伤口应用12毫升3%过氧化氢时,患者出现了肺栓塞的临床症状。立即开始对症治疗。当患者从麻醉中醒来时,出现了强直性惊厥。但他康复了,没有任何并发症。手术期间禁忌将过氧化氢注入闭合组织。