Antileukemic effects of pseudoisocytidine, a new synthetic pyrimidine C-nucleoside.
作者信息
Burchenal J H, Ciovacco K, Kalaher K, O'Toole T, Kiefner R, Dowling M D, Chu C K, Watanabe K A, Wempen I, Fox J J
出版信息
Cancer Res. 1976 Apr;36(4):1520-3.
PMID:1260769
Abstract
Pseudoisocytidine, a new synthetic pyrimidine C-nucleoside, which might be considered a more stable analog of 5-azacytidine, is active in vitro and in vivo, i.p. and p.o., against various 1-beta-D-arabinofuranosylcytosine-resistant lines of mouse leukemia. This antileukemic activity is blocked by cytidine but not by deoxycytidine or thymidine.
摘要
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