Melikian A G, Shakhnovich A R, Arutiunov N V
Zh Vopr Neirokhir Im N N Burdenko. 2002 Oct-Dec(4):5-11; discussion 11.
The paper presents data of a retrospective analysis of the outcomes of endoscopic ventriculostomy of the 3rd ventricle, obtained in a consecutive series of 120 patients aged 5 months to 58 years who had occlusive hydrocephalus and operated on at the Research Institute of Neurosurgery, Russian Academy of Medical Sciences, in 1995-2000. In most cases (n = 112), hydrocephalus was caused by a block at the level of the cerebral aqueduct. In more than 50% of the patients, different tumors were responsible for occlusion. In 96 (80%) cases, the operation led to the elimination of occlusion and to the regression of symptoms just after surgery. Complications were few and observed in 19 patients, ventriculitis (n = 7) and intracranial hemorrhages (n = 6) being most common. No death occurred. Seventy three patients were followed up for 1 month to 5 years (mean 1.5 years). Eliminated occlusion and steady-state remission were found in 64 (87.7%) cases. Improvement was strongly correlated with an increase in the reserve craniovertebral content capacity estimated by measuring the pulse amplitude of blood flow in the tentorial sinus in body position-changing tests. In 9 patients, the symptoms of hydrocephalus remained or recurred after short-term improvement. In 3 of them, this occurred with anatomically competent anastomoses between the 3rd ventricle and cisterns. In the other 6 cases, the obliteration and anatomic incompetence of ventriculostoma were responsible for a relapse. In 8 of the 9 patients, shunting had to be made subsequently in the period of 1 to 6 months. The paper also considers some biophysical aspects of cerebrospinal fluid circulation and discusses indications for endoscopy. It is concluded that endoscopic ventriculostomy of the 3rd ventricle is the method of choice in the treatment of patients with obstructive hydrocephalus.
本文介绍了对第三脑室内镜脑室造瘘术结果的回顾性分析数据,这些数据来自于1995年至2000年在俄罗斯医学科学院神经外科研究所接受手术的120例年龄在5个月至58岁之间的梗阻性脑积水患者。在大多数病例(n = 112)中,脑积水是由大脑导水管水平的梗阻引起的。超过50%的患者,梗阻是由不同肿瘤导致的。在96例(80%)病例中,手术在术后立即消除了梗阻并使症状消退。并发症较少,19例患者出现并发症,最常见的是脑室炎(n = 7)和颅内出血(n = 6)。无死亡病例。73例患者接受了1个月至5年的随访(平均1.5年)。64例(87.7%)病例中梗阻被消除且病情处于稳定缓解状态。改善情况与通过在体位改变试验中测量小脑幕窦血流脉冲幅度估算的颅椎内容物储备容量增加密切相关。9例患者脑积水症状在短期改善后仍持续或复发。其中3例,第三脑室与脑池之间解剖学上吻合良好却出现这种情况。另外6例中,脑室造瘘口闭塞及解剖学上不通畅是复发的原因。9例患者中有8例随后在1至6个月内不得不进行分流术。本文还考虑了脑脊液循环的一些生物物理学方面,并讨论了内镜检查的适应证。得出的结论是,第三脑室内镜脑室造瘘术是治疗梗阻性脑积水患者的首选方法。