一种预测儿童头部创伤后残疾情况的新方法的研发。

Development of a novel method to predict disability after head trauma in children.

作者信息

Cassidy Laura D, Potoka Douglas A, Adelson P David, Ford Henri R

机构信息

Department of Surgery, University of Pittsburgh and Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

出版信息

J Pediatr Surg. 2003 Mar;38(3):482-5. doi: 10.1053/jpsu.2003.50084.

Abstract

BACKGROUND/PURPOSE: Although analysis of functional independence measures (FIM) at discharge are useful for assessing extent of disability in head-injured children, there is no reliable method to predict the severity of disability at the time of admission. The authors developed a novel method to predict severe disability after head trauma on admission.

METHODS

Head-injured patients, 2 to 16 years old, with FIM recorded at discharge (n = 3,491) were identified in our state trauma database for the period from 1993 through 1996. Patients categorized as completely dependent by one or more of the FIM (Feeding, Locomotion, Expression, Transfer Mobility, Social Interaction) were classified as disabled. Probability of disability (P(D)) was estimated based on regression weights for Glasgow Coma Scale (GCS), Injury Severity Score (ISS), age, and number of anatomic regions injured. Observed to expected disability rates were compared using a test data set of 2,553 patients entered in the database between 1997 through 1999.

RESULTS

There was no statistically significant difference between observed and expected disability across all P(D) intervals, which suggests that the P(D) accurately predicted disability.

CONCLUSIONS

P(D) offers a novel and reliable method for early prediction of likelihood of disability in children who sustain head trauma. Routine use of the P(D) may lead to earlier intervention to improve long-term results in head-injured children.

摘要

背景/目的:尽管出院时功能独立性测量(FIM)分析有助于评估头部受伤儿童的残疾程度,但目前尚无可靠方法预测入院时的残疾严重程度。作者开发了一种新方法来预测头部创伤入院后严重残疾的情况。

方法

在我们的州创伤数据库中,识别出1993年至1996年期间2至16岁、出院时记录了FIM(喂食、移动、表达、转移活动、社交互动)的头部受伤患者(n = 3491)。被FIM中的一项或多项归类为完全依赖(喂食、移动、表达、转移活动、社交互动)的患者被归类为残疾。基于格拉斯哥昏迷量表(GCS)、损伤严重程度评分(ISS)、年龄和受伤解剖区域数量的回归权重估计残疾概率(P(D))。使用1997年至1999年输入数据库的2553例患者的测试数据集比较观察到的和预期的残疾率。

结果

在所有P(D)区间内,观察到的和预期的残疾之间没有统计学上的显著差异,这表明P(D)准确预测了残疾情况。

结论

P(D)为早期预测头部受伤儿童残疾可能性提供了一种新颖且可靠的方法。常规使用P(D)可能会导致更早进行干预,以改善头部受伤儿童的长期预后。

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