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术前禁食与肺误吸。新观点与指南。

Preoperative starvation and pulmonary aspiration. New perspectives and guidelines.

作者信息

Scarlett M, Crawford-Sykes A, Nelson M

机构信息

Department of Surgery, Radiology, Anaesthesia and Intensive Care, University of the West Indies, Kingston 7, Jamaica.

出版信息

West Indian Med J. 2002 Dec;51(4):241-5.

Abstract

The fear of aspiration of gastric contents and its life-threatening consequences in patients(aspiration pneumonitis and respiratory failure), has caused many medical practitioners, particularly anaesthetists, to rigidly follow conservative (i.e. prolonged) preoperative fasting standards. This is the nil per os (NPO) order for clear fluids/liquids and solids overnight or six to eight hours preceding the induction of anaesthesia. This practice neither takes into account the differences in the rate of gastric emptying for solid food (which may exceed six hours) and clear liquids (which is one to two hours), nor the differences in scheduled times of surgery. Long-term prospective studies and retrospective reviews have shown that the incidence of significant clinical aspiration is low: 1.4-6.0 per 100,00 anaesthetics for elective general surgery. Risk factors for pulmonary aspiration include: a high American Society of Anaesthesiologists (ASA) physical status score; emergency surgery; difficult airway management; increased gastric volume and acidity; increased intra-abdominal pressure; gastro-oesophageal reflux; oesophageal disease; head injury with impaired consciousness and extremes of age. Experimental studies and reviews have consistently shown the safety of clear liquid ingestion up to two hours before induction of anaesthesia in healthy patients without risk factors, and the fact that a longer fluid fast does not necessarily offer any added protection against pulmonary aspiration. The conservative pre-operative fasting standard causes discomfort and in some cases, suffering of patients and is therefore unnecessary for patients without risk factor(s). Anecdotal reports at the University Hospital of the West Indies (UHWI) have shown that application of the liberalized guidelines for preoperative fasting and fluid intake has not resulted in increased pulmonary aspiration, morbidity or mortality. Instead it has resulted in decreased irritability, anxiety, thirst and hunger in the peri-operative period. Patients, especially children are more comfortable and the perioperative period is better tolerated. It is therefore time that all medical personnel adopt the liberalized guidelines.

摘要

担心患者胃内容物误吸及其危及生命的后果(误吸性肺炎和呼吸衰竭),导致许多医生,尤其是麻醉医生严格遵循保守的(即延长的)术前禁食标准。这就是术前禁食医嘱,即麻醉诱导前一晚或六至八小时禁食清液/液体和固体食物。这种做法既没有考虑固体食物(可能超过六小时)和清液(一至两小时)胃排空速率的差异,也没有考虑手术预定时间的差异。长期前瞻性研究和回顾性分析表明,严重临床误吸的发生率较低:择期普通外科手术每10000例麻醉中为1.4 - 6.0例。肺误吸的危险因素包括:美国麻醉医师协会(ASA)身体状况评分高;急诊手术;气道管理困难;胃容量和酸度增加;腹内压升高;胃食管反流;食管疾病;意识受损的头部损伤以及极端年龄。实验研究和综述一致表明,对于没有危险因素的健康患者,麻醉诱导前两小时摄入清液是安全的,而且禁食时间延长不一定能为预防肺误吸提供更多保护。保守的术前禁食标准会给患者带来不适,在某些情况下还会造成痛苦,因此对于没有危险因素的患者来说是不必要的。西印度群岛大学医院(UHWI)的轶事报告显示,应用放宽的术前禁食和液体摄入指南并未导致肺误吸、发病率或死亡率增加。相反,它减少了围手术期的易怒、焦虑、口渴和饥饿感。患者,尤其是儿童感觉更舒适,对围手术期的耐受性更好。因此,现在是所有医务人员采用放宽指南的时候了。

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