再生障碍性贫血患者在接受抗胸腺细胞球蛋白和环孢素治疗后发生默克尔细胞癌。
Merkel cell carcinoma developing after antithymocyte globulin and cyclosporine therapy for aplastic anemia.
作者信息
Takabayashi Maki, Sakai Rika, Sakamoto Hiroshi, Iemoto Youichi, Kanamori Heiwa, Inayama Yoshiaki, Ishigatsubo Yoshiaki
机构信息
Department of Hematology/Immunology, Fujisawa City Hospital, Fujisawa, Japan.
出版信息
Anticancer Drugs. 2003 Mar;14(3):251-3. doi: 10.1097/00001813-200303000-00010.
We report a patient who developed Merkel cell carcinoma (MCC) after treatment with antithymocyte globulin and cyclosporine for aplastic anemia. The clinical course was progressive and poor prognosis. Although MCC is relatively rare in second cancers arising after immunosuppressive therapy, patients should be closely monitored for the development of this complication as well as other second malignancies.
我们报告了一名再生障碍性贫血患者，在接受抗胸腺细胞球蛋白和环孢素治疗后发生了默克尔细胞癌（MCC）。临床病程呈进行性，预后较差。尽管MCC在免疫抑制治疗后发生的第二癌症中相对罕见，但仍应密切监测患者是否发生这种并发症以及其他第二恶性肿瘤。
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