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[梅毒性主动脉炎患者合并双侧冠状动脉开口狭窄及主动脉瓣反流]

[Bilateral coronary ostial stenoses with aortic regurgitation in a patient with syphilitic aortitis].

作者信息

Tsukui H, Koh E, Yokoyama S, Ogawa M, Kato G, Saitoh H

机构信息

Department of Cardiovascular Surgery, Kyoto Second Red Cross Hospital, Kyoto, Japan.

出版信息

Kyobu Geka. 2003 Feb;56(2):158-60.

Abstract

Syphilitic aortitis is now rare in developed countries and is sometimes overlooked. A 61-year-old man with bilateral coronary ostial stenoses (#5:90%, #1:99%) and Sellers III/IV aortic regugitatioin (AR) induced by syphilitic aortitis presented with chest pain. Preoperative rapid plasma reagin titer and Treponema pallidum hemagglutination test were strongly positive, 256 fold and 191.25 C.O.I., respectively. Aortic valve replacement (AVR) and coronary artery bypass grafting (CABG) with bilateral internal thoracic arteries (ITA) was performed successfully. The angiographic features as follows: 1) coronary artery stenosis is generally limited to the ostia, 2) the grade of stenosis is almost always more than 90%, 3) AR is frequently associated with coronary ostial stenosis. CABG should be performed with ITA, not saphenous vein grafts, to avoid occlusion of the ostium of the saphenous vein graft by syphilitic aortitis. Retrograde cardioplegia should be performed if ostial stenosis is severe.

摘要

梅毒性主动脉炎在发达国家现已罕见,有时会被忽视。一名61岁男性因梅毒性主动脉炎导致双侧冠状动脉开口狭窄(5号冠状动脉:90%,1号冠状动脉:99%)及 Sellers III/IV 级主动脉瓣反流(AR),出现胸痛症状。术前快速血浆反应素滴度和梅毒螺旋体血凝试验均呈强阳性,分别为256倍和191.25 COI。成功进行了主动脉瓣置换术(AVR)和双侧胸廓内动脉(ITA)冠状动脉旁路移植术(CABG)。血管造影特征如下:1)冠状动脉狭窄通常局限于开口处;2)狭窄程度几乎总是超过90%;3)主动脉瓣反流常与冠状动脉开口狭窄相关。应使用胸廓内动脉而非大隐静脉进行冠状动脉旁路移植术,以避免梅毒主动脉炎导致大隐静脉移植开口闭塞。如果开口狭窄严重,应采用逆行心脏停搏。

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