Shaffrali Freida C G, Colver Graham B, Messenger Andrew G, Gawkrodger David J
Departments of Dermatology, Royal Hallamshire Hospital, Sheffield, England.
J Am Acad Dermatol. 2003 Mar;48(3):417-9. doi: 10.1067/mjd.2003.137.
There is very little published information on the use of methotrexate in treating eczema. We have used methotrexate in 5 elderly patients with eczema, with a successful response in 4; in 1 patient therapy was stopped as a result of other ongoing medical problems. Methotrexate can be considered as an option in the treatment of eczema unresponsive to topical therapy in elderly patients.