使用光纤耦合闪烁体的生物医学探针。

Biomedical probe using a fiber-optic coupled scintillator.

作者信息

Swinth K L, Ewins J H

出版信息

Med Phys. 1976 Mar-Apr;3(2):109-12. doi: 10.1118/1.594274.

Abstract

A high-sensitivity biomedical radiation probe which employs a fiber-optic coupled NaI(Tl) scintillator as a detector is described. It was developed for in vivo counting of low-energy 239Pu photons from material located in the tracheobronchial lymph nodes.-This probe is 20 times as sensitive as a solid-state probe (avalanche diode) previously developed for this application. Tests with 99mTc show a sensitivity more than 90 times greater than biomedical probes using DcTe of GaAs; however, the improved sensitivity is largely due to an increased sensitive volume. Probes were evaluated in animals and phantoms for detection of 239Pu and for location of lung tumors labeled with 111In.

摘要

描述了一种高灵敏度生物医学辐射探测器，它采用光纤耦合碘化钠（铊）闪烁体作为探测器。该探测器是为对气管支气管淋巴结中物质产生的低能钚-239光子进行体内计数而研制的。这种探测器的灵敏度是先前为此应用开发的固态探测器（雪崩二极管）的20倍。用锝-99m进行的测试表明，其灵敏度比使用砷化镓碲化镉的生物医学探测器高90多倍；然而，灵敏度的提高主要是由于敏感体积的增加。在动物和模型中对探测器进行了评估，以检测钚-239并定位用铟-111标记的肺部肿瘤。