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足月前后至18个月头围生长的距离和速度标准——一项纵向研究的结果(作者译)

[Distance and velocity standards for head circimference growth before and after term until 18 months--results from a longitudinal study (author's transl)].

作者信息

Brandt I

出版信息

Monatsschr Kinderheilkd (1902). 1976 Apr;124(4):141-50.

PMID:1264088
Abstract

Standards for head circumference growth (distance and velocity) from the perinatal period until the age of 18 months have been based on repeated measurements at short intervals (longitudinal) in 60 appropriate for gestational age (AGA) preterm infants of very low fetal age, and 68 full term infants. Moreover the growth of 32 small for gestational age (SGA) preterm infants has been evaluated. Before term the extrauterine head growth curve is similar to that of "intrauterine curves". At term and until the age of 18 months the growth curves of AGA preterm infants agree well with those of the full term controls, without statistically significant differences (p greater than 0.1). If the age is not corrected for prematurity ther is a significant difference between preterm and full term infants until 17 months (p less than 0.05). With decreasing velocity of head circumference growth this difference becomes non-significant at the age of 18 months (p greater than 0.1). Out of the heterogenious group of 32 SGA preterm infants 15 have shown a catch-up growth in head circumference until the third month, whereas 17 infants remained significantly below the growth curve of the AGA. Growth velocity of head circumference, calculated in cm/month, in the last 10 weeks before term is significantly higher (p less 0.025) than later on, with a mean peak of 4.3 cm in the 34th postmentstrual week. After term, the velocity curve of the AGA preterm infants agrees with that of the full term controls. A period of rapid head circumference growth -- a growth spurt -- extends from the 31st postmenstrual week until the 6th month after term. In the following months the velocity curves flatten. If the age is not corrected for prematurity, the peak of the velocity curve becomes flat and spread with a mean growth velocity of 3.0 cm in the first, of 3.4 cm in the second and of 2.5 cm in the third month.

摘要

从围产期到18个月龄的头围生长标准(距离和速度)基于对60名胎龄极低的适于胎龄(AGA)早产儿和68名足月儿进行的短间隔重复测量(纵向测量)。此外,还评估了32名小于胎龄(SGA)早产儿的生长情况。在足月前,宫外头围生长曲线与“宫内曲线”相似。足月时及直到18个月龄,AGA早产儿的生长曲线与足月对照者的生长曲线吻合良好,无统计学显著差异(p大于0.1)。如果未对早产进行年龄校正,直到17个月时早产儿与足月儿之间存在显著差异(p小于0.05)。随着头围生长速度降低,这种差异在18个月龄时变得不显著(p大于0.1)。在32名异质性SGA早产儿中,15名在第三个月前头围出现追赶生长,而17名婴儿仍显著低于AGA的生长曲线。在足月前的最后10周,以厘米/月计算的头围生长速度显著高于之后(p小于0.025),在月经后第34周平均峰值为4.3厘米。足月后,AGA早产儿的速度曲线与足月对照者的曲线一致。快速头围生长期——生长突增期——从月经后第31周持续到足月后第6个月。在接下来的几个月里,速度曲线变平。如果未对早产进行年龄校正,速度曲线的峰值变平且变宽,第一个月平均生长速度为3.0厘米,第二个月为3.4厘米,第三个月为2.5厘米。

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