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性类固醇激素与眼睛的相互作用。

Pinteraction of sex steroid hormones with the eye.

作者信息

Gupta Purshottam D, Kalariya Nilesh, Nagpal Kamal, Vasavada Abhay

机构信息

Institute Iladevi Cataract and IOL Research Centre, Raghudeep Eye Clinic, Gurukul Memnagar, Ahmedabad 380 052, India.

出版信息

Cell Mol Biol (Noisy-le-grand). 2002;48 Online Pub:OL379-86.

Abstract

Many epidemiologic and laboratory studies in the recent past suggested that the physiology of the eye may be affected by alterations in sex steroid homeostasis due to ageing and pathogenesis. This hypothesis is again strengthened by the presence of specific receptors for steroid hormones in various ocular tissues. However their involvement in pathological process is not yet clearly established. This review deals with a viewpoint on the possible beneficial and detrimental effects of sex steroids on ocular physiopathology. Since sex steroids are different in males and females, an interesting concept of sexual dimorphism in human eye also emerges from this information.

摘要

近期许多流行病学和实验室研究表明,由于衰老和发病机制导致的性类固醇稳态改变可能会影响眼睛的生理功能。各种眼部组织中存在类固醇激素的特定受体,这一假说再次得到了证实。然而,它们在病理过程中的作用尚未明确。这篇综述探讨了性类固醇对眼部生理病理学可能产生的有益和有害影响的观点。由于男性和女性的性类固醇不同,从这些信息中还引出了人眼性二态性这一有趣的概念。

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