Novel alpha-amino-acid phenolic ester derivatives with intravenous anaesthetic activity.
作者信息
Cooke Andrew, Anderson Alison, Bennett Jonathan, Buchanan Kirsteen, Gemmell David, Hamilton Niall, Maidment Maurice, McPhail Petula, Stevenson Donald, Sundaram Hardy
机构信息
Department of Medicinal Chemistry, Organon Laboratories Ltd., Newhouse, Scotland, ML1 5SH, UK.
出版信息
Bioorg Med Chem Lett. 2003 Mar 24;13(6):1107-10. doi: 10.1016/s0960-894x(03)00025-8.
Abstract
A novel series of alpha-amino-acid phenolic ester derivatives containing sulphide, sulphoxide, sulphone, ester and amide side chains were prepared and shown to display potent intravenous anaesthetic activity.
摘要
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