Lin Jiangkai, Feng Hua, Li Fei, Zhao Bingmei, Guo Qiaonan
Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Shapingba District, Chongqing, People's Republic of China.
J Neurosurg. 2003 Mar;98(3):621-4. doi: 10.3171/jns.2003.98.3.0621.
A 48-year-old man presented with a rare intraparenchymal schwannoma of the medulla oblongata. After he underwent gamma knife surgery, the patient's condition deteriorated and the mass, which at the time was thought to be a glioma, became larger on magnetic resonance images. The mass was resected through a suboccipital craniectomy via the transcerebellomedullary fissure approach. The tumor, which was moderately firm but distinct from the surrounding parenchyma, was removed totally. Postoperative histological and immunohistochemical examinations confirmed the diagnosis of a benign schwannoma. Brainstem schwannomas can be cured by microneurosurgery. It is important to distinguish these tumors from glioma. The main theories on the cause(s) of this lesion are briefly reviewed.
一名48岁男性患者,患有罕见的延髓实质内神经鞘瘤。在接受伽玛刀手术后,患者病情恶化,当时被认为是胶质瘤的肿块在磁共振图像上变得更大。通过经小脑延髓裂入路的枕下开颅术切除了肿块。肿瘤质地中等坚实,但与周围实质不同,被完全切除。术后组织学和免疫组化检查确诊为良性神经鞘瘤。脑干神经鞘瘤可通过显微神经外科手术治愈。将这些肿瘤与胶质瘤区分开来很重要。本文简要回顾了关于该病变病因的主要理论。