Yang Ya, Bartel Thomas, Eggebrecht Holger, Latina Loredana, von Birgelen Clemems, Caspari Guido, Wang Xinfang, Erbel Raimund
Institute of Cardiovascular Disease, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
J Huazhong Univ Sci Technolog Med Sci. 2002;22(2):158-63. doi: 10.1007/BF02857683.
Transthoracic Doppler echocardiography (TTDE) allows noninvasive flow measurement in the distal left anterior descending artery (LAD). The feasibility of detecting coronary flow by contrast-enhanced TTDE with second harmonic technique was assessed, the coronary flow velocity reserve (CFVR) was evaluated in comparison to intracoronary Doppler flow (ICD) analysis and the CFVR after PTCA in LAD was investigated. In 77 (96%) of 80 patients, CFVR was successfully determined with intravenous adenosine infusion. Doppler signal quality was evaluated in the first 46 patients by use of intravenous Levovist infusion and second harmonic technique. The Doppler flow was not visible in 1. patient only. CFVR determined from TTDE (2.77 +/- 0.65) was correlated closely with those from ICD (2.88 +/- 0.78) measurements (y = 0.73x + 0.67, r = 0.87, P < 0.001). In conclusion, TTDE is a feasible method and provides reliable data on CFVR which can be used for follow-up after PTCA.
经胸多普勒超声心动图（TTDE）可对左前降支（LAD）远端进行无创血流测量。评估了采用二次谐波技术的对比增强TTDE检测冠状动脉血流的可行性，与冠状动脉内多普勒血流（ICD）分析相比评估了冠状动脉血流储备（CFVR），并研究了LAD经皮冠状动脉腔内血管成形术（PTCA）后的CFVR。80例患者中的77例（96%）通过静脉注射腺苷成功测定了CFVR。在前46例患者中，使用静脉注射声诺维并采用二次谐波技术评估了多普勒信号质量。仅1例患者未检测到多普勒血流。TTDE测定的CFVR（2.77±0.65）与ICD测定的CFVR（2.88±0.78）密切相关（y = 0.73x + 0.67，r = 0.87，P < 0.001）。总之，TTDE是一种可行的方法，可提供关于CFVR的可靠数据，可用于PTCA后的随访。
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