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Chemical genomics of orphan nuclear receptors.

作者信息

Willson T

机构信息

GlaxoSmithKline North Carolina, 5 Moore Drive, Research Triangle Park, North Carolina, NC 27709, USA.

出版信息

Ernst Schering Res Found Workshop. 2003(42):29-42. doi: 10.1007/978-3-662-05314-0_4.

DOI:10.1007/978-3-662-05314-0_4

PMID:12664534

Abstract

摘要

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Chemical genomics of orphan nuclear receptors.

作者信息

Willson T

机构信息

GlaxoSmithKline North Carolina, 5 Moore Drive, Research Triangle Park, North Carolina, NC 27709, USA.

出版信息

Ernst Schering Res Found Workshop. 2003(42):29-42. doi: 10.1007/978-3-662-05314-0_4.

DOI:10.1007/978-3-662-05314-0_4

PMID:12664534

Abstract

摘要

相似文献

Chemical genomics of orphan nuclear receptors.

Ernst Schering Res Found Workshop. 2003(42):29-42. doi: 10.1007/978-3-662-05314-0_4.

Genomics versus orphan nuclear receptors--a half-time report.

Mol Endocrinol. 2002 Jun;16(6):1135-44. doi: 10.1210/mend.16.6.0849.

Orphan nuclear receptors adopted by crystallography.

Curr Opin Struct Biol. 2005 Dec;15(6):708-15. doi: 10.1016/j.sbi.2005.10.009. Epub 2005 Nov 2.

RORalpha: an orphan nuclear receptor on a high-cholesterol diet.

Structure. 2002 Dec;10(12):1605-6. doi: 10.1016/s0969-2126(02)00916-4.

Design and synthesis of receptor ligands.

Methods Enzymol. 2003;364:71-91. doi: 10.1016/s0076-6879(03)64005-x.

Digging deep into the pockets of orphan nuclear receptors: insights from structural studies.

Trends Cell Biol. 2004 Jul;14(7):369-76. doi: 10.1016/j.tcb.2004.05.007.

A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1).

J Mol Biol. 2016 Dec 4;428(24 Pt B):4981-4992. doi: 10.1016/j.jmb.2016.10.025. Epub 2016 Oct 27.

Nuclear receptors. How to finger DNA.

Nature. 1995 May 18;375(6528):190-1. doi: 10.1038/375190a0.

Allosteric controls of nuclear receptor function in the regulation of transcription.

J Mol Biol. 2013 Jul 10;425(13):2317-29. doi: 10.1016/j.jmb.2013.03.017. Epub 2013 Mar 15.

Carboxylic acid based quinolines as liver X receptor modulators that have LXRbeta receptor binding selectivity.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):54-9. doi: 10.1016/j.bmcl.2007.11.013. Epub 2007 Nov 9.

引用本文的文献

Unique mode of lipogenic activation in rat preputial sebocytes.

J Nutr Metab. 2011;2011:163631. doi: 10.1155/2011/163631. Epub 2011 Jul 26.

Arginase I induction by modified lipoproteins in macrophages: a peroxisome proliferator-activated receptor-gamma/delta-mediated effect that links lipid metabolism and immunity.

Mol Endocrinol. 2008 Jun;22(6):1394-402. doi: 10.1210/me.2007-0525. Epub 2008 Mar 6.

J Neurosci. 2003 Oct 29;23(30):9796-804. doi: 10.1523/JNEUROSCI.23-30-09796.2003.