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皮质类固醇注射治疗桡骨茎突狭窄性腱鞘炎:一项汇总定量文献评估

Corticosteroid injection for treatment of de Quervain's tenosynovitis: a pooled quantitative literature evaluation.

作者信息

Richie Carlton A, Briner William W

机构信息

Lutheran General Hospital Sports Medicine Center, Park Ridge, Ill, USA.

出版信息

J Am Board Fam Pract. 2003 Mar-Apr;16(2):102-6. doi: 10.3122/jabfm.16.2.102.

DOI:10.3122/jabfm.16.2.102
PMID:12665175
Abstract

BACKGROUND

There have been many approaches described to treat de Quervain's tenosynovitis, but no definite consensus emerges in the literature. We conducted a pooled quantitative literature evaluation to review the therapeutic studies in the English language to determine the various reported cure rates.

METHODS

All citations in the MEDLINE and Ovid databases that addressed de Quervain's tenosynovitis were independently reviewed. Appropriate studies from the bibliographies of these articles were then obtained. Of the 35 articles on de Quervain's temosynovitis that were found in the modern literature, only seven allowed for comparison among potentially effective treatments. Studies were included if they evaluated or compared treatment options among patients and had defined criteria for diagnosis and successful treatment. These seven studies were descriptive, not comparative. In other words, each study reported the proportion of successful outcomes with different treatments, without a comparison to a specified control group. Four hundred fifty-nine wrists were subjected to one of several therapeutic modalities.

RESULTS

There was an 83% cure rate with injection alone. This rate was much higher than any other therapeutic modality (61% for injection and splint, 14% for splint alone, 0% for rest or nonsteroidal anti-inflammatory drugs).

CONCLUSION

It seems that injection alone is the best therapeutic approach to de Quervain's tenosynovitis.

摘要

背景

已有多种治疗桡骨茎突狭窄性腱鞘炎的方法被描述,但文献中尚未形成明确的共识。我们进行了一项汇总定量文献评估,以回顾英文的治疗研究,从而确定各种报道的治愈率。

方法

对MEDLINE和Ovid数据库中所有涉及桡骨茎突狭窄性腱鞘炎的文献进行独立审查。然后从这些文章的参考文献中获取合适的研究。在现代文献中找到的35篇关于桡骨茎突狭窄性腱鞘炎的文章中,只有7篇允许对潜在有效的治疗方法进行比较。如果研究评估或比较了患者之间的治疗选择,并且有明确的诊断和成功治疗标准,则纳入研究。这7项研究是描述性的,而非比较性的。换句话说,每项研究报告了不同治疗方法的成功结果比例,而没有与特定对照组进行比较。459例手腕接受了几种治疗方式中的一种。

结果

仅注射治疗的治愈率为83%。该治愈率远高于任何其他治疗方式(注射加夹板固定为61%,仅夹板固定为14%,休息或使用非甾体抗炎药为0%)。

结论

对于桡骨茎突狭窄性腱鞘炎,似乎仅注射治疗是最佳的治疗方法。

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