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纽约市学童的结核菌素试验与结核感染风险

Tuberculin testing and risk of tuberculosis infection among New York City schoolchildren.

作者信息

Gounder Celine R, Driver Cynthia R, Scholten Jerod N, Shen Huimin, Munsiff Sonal S

机构信息

Tuberculosis Control Program, New York City Department of Health, New York, New York 10007, USA.

出版信息

Pediatrics. 2003 Apr;111(4 Pt 1):e309-15. doi: 10.1542/peds.111.4.e309.

Abstract

OBJECTIVES

To assess adherence to a 1996 health policy change, which discontinued mandatory tuberculin skin testing (TST) of new entrants to NYC primary schools and continued mandatory testing of new entrants to secondary schools.

METHODS

The proportion tested before (1991-1995) and after (1996-1998) the change in health policy was determined. Factors associated with TST positivity and the cost of continued testing were assessed.

RESULTS

A total of 76.6% of 551 636 new entrants to primary schools were tested in 1991-1995; slightly fewer, 71.1% of 339 958, were tested in 1996- 1998. Among new entrants to secondary schools, 31.0% of 106 463 were tested in 1991-1995 and 51.4% of 53 762 were tested in 1996-1998. The proportion who were TST-positive continued to decrease after 1996 to 1.2% among primary and 9.7% among secondary schoolchildren in 1998. Older age and birth outside the United States were associated with TST positivity. The estimated minimum cost of continued testing in primary schools was $123 152 per tuberculosis case prevented.

CONCLUSION

An approach aimed at reducing testing of children at low risk for latent tuberculosis infection did not decrease testing of younger children. More important, older children who were more likely to be born in countries of high tuberculosis incidence were not tested. Additional efforts are needed to increase awareness among medical and school personnel to decrease testing among children who do not have risk factors for latent tuberculosis infection and to increase tuberculin testing of children who are entering school for the first time at the secondary level and do have risk factors for tuberculosis infection.

摘要

目的

评估对1996年一项卫生政策变化的依从性,该政策停止了对纽约市小学新入学儿童进行强制性结核菌素皮肤试验(TST),但继续对中学新入学儿童进行强制性检测。

方法

确定卫生政策变化之前(1991 - 1995年)和之后(1996 - 1998年)进行检测的比例。评估与TST阳性相关的因素以及继续检测的成本。

结果

1991 - 1995年,551636名小学新入学儿童中有76.6%接受了检测;1996 - 1998年,339958名儿童中接受检测的比例略低,为71.1%。在中学新入学儿童中,1991 - 1995年106463名中有31.0%接受了检测,1996 - 1998年53762名中有51.4%接受了检测。1996年后,TST呈阳性的比例继续下降,1998年小学儿童中为1.2%,中学儿童中为9.7%。年龄较大以及在美国境外出生与TST阳性相关。小学继续检测预防每例结核病的估计最低成本为123152美元。

结论

旨在减少对潜伏性结核感染低风险儿童检测的方法并未减少对年幼儿童的检测。更重要的是,那些更有可能出生在结核病高发国家的大龄儿童未接受检测。需要做出更多努力,提高医疗和学校工作人员的认识,以减少对无潜伏性结核感染风险因素儿童的检测,并增加对首次进入中学且有结核感染风险因素儿童的结核菌素检测。

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