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睾丸决定需要Dax1。

Dax1 is required for testis determination.

作者信息

Meeks Joshua J, Weiss Jeffrey, Jameson J Larry

机构信息

Division of Endocrinology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

出版信息

Nat Genet. 2003 May;34(1):32-3. doi: 10.1038/ng1141.

Abstract

The orphan nuclear receptor, Dax1, was originally proposed to act as an 'anti-testis' factor. We find, however, that Nr0b1 (also called Dax1 and Ahch, which encodes Dax1) is in fact required for testis differentiation.

摘要

孤儿核受体Dax1最初被认为是一种“抗睾丸”因子。然而,我们发现,Nr0b1(也称为Dax1和Ahch,其编码Dax1)实际上是睾丸分化所必需的。

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