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耳硬化症的流行病学方面(二):性别、遗传因素、诊断前病程、诊断年龄及其起始年龄

[Epidemiological aspects of otosclerosis (II): sex, hereditary factors, its course before diagnosis, age at diagnosis and its beginning].

作者信息

Cajade Frías J, Labella Caballero T

机构信息

Servicio ORL, Hospital Provincial de Conxo, Complejo Hospitalario Universitario, Santiago de Compostela.

出版信息

An Otorrinolaringol Ibero Am. 2003;30(1):17-30.

Abstract

Retrospective study done with a group of 401 patients enduring otosclerosis. Seventy percent were women. 59% with positive familial antecedents. Illness was recognized as midpoint, at 44.5 years and symptomatology started at 35.3 years. Lasting time of condition till diagnosis assured was 8.5 years (higher than 5 years the half of cases and between 1 an 5 years the third part of them), these numbers considerably decreasing regarding other older series. Figures lower in those cases without familiar otosclerotic antecedents, the same than in unilateral specimen. The only significative influence of sex where tinnitus aurium among women (70.7% to face up 51.7%).

摘要

对一组401例耳硬化症患者进行了回顾性研究。其中70%为女性,59%有阳性家族史。疾病确诊的中位年龄为44.5岁,症状出现年龄为35.3岁。从病情出现到确诊的持续时间为8.5年(半数病例超过5年,三分之一病例在1至5年之间),与其他较早的系列研究相比,这些数字有显著下降。在无家族性耳硬化病史的病例中,以及单侧病例中,这些数字更低。性别方面唯一有显著影响的是女性的耳鸣发生率(70.7%,而男性为51.7%)。

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