Brien T G, Dalrymple I J
Br J Obstet Gynaecol. 1976 May;83(5):361-7. doi: 10.1111/j.1471-0528.1976.tb00843.x.
Total plasma cortisol, the 'cortisol resin uptake ratio' (cortisol RUR), and 'free cortisol index' (FCI) were estimated in 23 pregnant women from 12 weeks to term and at six weeks post partum. Total plasma cortisol rose continually throughout pregnancy; the cortisol RUR rose up to 20 to 23 weeks and then fell slowly and the FCI also rose although more slowly than the total cortisol. All parameters fell to non-pregnant levels at six weeks post partum. It is confirmed that a true rise in metabolically active cortisol occurs during pregnancy.
对23名孕妇在孕12周直至足月以及产后6周时的血浆总皮质醇、“皮质醇树脂摄取率”(皮质醇RUR)和“游离皮质醇指数”(FCI)进行了评估。整个孕期血浆总皮质醇持续上升;皮质醇RUR在20至23周时上升,然后缓慢下降,FCI也上升,不过比总皮质醇上升得更缓慢。产后6周时,所有参数均降至非孕期水平。证实孕期代谢活性皮质醇确实会升高。