Pellengahr C, Mayer W, Maier M, Müller P E, Schulz C, Dürr H R, Trouillier H, Steinborn M, Jansson V, Refior H J
Department of Orthopaedic Surgery, Klinikum Grosshadern, Ludwig Maximilians University Munich, Marchioninistrasse 15, 81377 Munich, Germany.
Arch Orthop Trauma Surg. 2003 May;123(4):139-43. doi: 10.1007/s00402-002-0429-0. Epub 2003 Apr 10.
The problem of metal sensitivity (Ni, Cr, and Co) in arthroplasty is still unsolved. To prevent the risk of allergy in cases with proved metal allergy in an epicutaneous test, a Natural Knee total knee arthroplasty, made totally from titanium (Ti-6Al-4V) and polyethylene, can be implanted. The results of this device have to be compared to the results of normal knee arthroplasty designed with a femoral component out of CrCoNi alloy. The mechanical resistance of this alloy is much higher than that of titanium, and therefore it is the standard for the femoral components of most knee-resurfacing devices.
Thirty-five patients with a titanium Natural Knee were examined retrospectively after a mean follow-up of 2 years and 5 months (range 6 months to 5 years and 4 months). In comparison, 36 patients with a Genesis-I knee with a CrCoNi alloy femoral component were studied after a mean follow-up of 2 years and 4 months (range 8 months to 6 years and 2 months).
In spite of the lower mechanical resistance of titanium, the Natural Knee showed better results (knee score 84.1 points, function score 77.7 points, HSS score 80.1 points, 82.9% excellent and good results) than the Genesis-I knee (knee score 80.6 points, function score 76.4 points, HSS score 76.4 points, 68.5% excellent and good results), although these differences had no statistical significance.
The titanium Natural Knee prosthesis has proven to be a reliable knee joint replacement in the medium term.
关节置换术中金属过敏(镍、铬和钴)问题仍未解决。为防止经表皮试验证实存在金属过敏的病例发生过敏风险,可植入一种完全由钛(Ti - 6Al - 4V)和聚乙烯制成的自然膝关节全膝关节置换假体。该假体的结果必须与采用铬钴镍合金股骨部件设计的普通膝关节置换术的结果进行比较。这种合金的机械强度远高于钛,因此是大多数膝关节表面置换装置股骨部件的标准材料。
对35例植入钛制自然膝关节假体的患者进行回顾性研究,平均随访时间为2年零5个月(范围为6个月至5年零4个月)。作为对照,对36例植入Genesis - I型膝关节假体(带有铬钴镍合金股骨部件)的患者进行研究,平均随访时间为2年零4个月(范围为8个月至6年零2个月)。
尽管钛的机械强度较低,但自然膝关节假体的效果(膝关节评分84.1分,功能评分77.7分,HSS评分80.1分,优良率82.9%)优于Genesis - I型膝关节假体(膝关节评分80.6分,功能评分76.4分,HSS评分76.4分,优良率68.5%),不过这些差异无统计学意义。
钛制自然膝关节假体已被证明在中期是一种可靠的膝关节置换物。