类风湿关节炎患者骨科手术的使用情况在下降?一项基于人群的长期评估结果。

Declining use of orthopedic surgery in patients with rheumatoid arthritis? Results of a long-term, population-based assessment.

作者信息

da Silva Eleonora, Doran Michele F, Crowson Cynthia S, O'Fallon W Michael, Matteson Eric L

机构信息

Universidade Federale de Sao Paulo, Brazil.

出版信息

Arthritis Rheum. 2003 Apr 15;49(2):216-20. doi: 10.1002/art.10998.

Abstract

OBJECTIVE

To describe the use of orthopedic surgery, including joint replacement surgery, in a well-defined, population-based cohort of patients with rheumatoid arthritis (RA) and to identify characteristics that predict such use.

METHODS

A retrospective medical record review was performed of cases of RA incident in Rochester, Minnesota, during the years 1955-1995. All joint surgeries were recorded.

RESULTS

Of the total 609 RA incident cases, 242 patients underwent 1 or more (maximum of 20/patient) surgical procedures involving joints during their followup. Overall, this RA cohort had 7.4 surgeries per 100 person-years of followup; the cumulative incidence for joint surgery for RA-related joint disease at 30 years was 33.7% +/- SEM 3.8%. The risk of having a disease-related joint surgery for RA is increased in patients who are women, younger, positive for rheumatoid factor, and have rheumatoid nodules. When adjusted for duration of followup, patients with RA diagnosed after 1985 were significantly less likely to have undergone joint surgery for RA (P < 0.001). Survival of patients who underwent total joint arthroplasty was similar to those who did not.

CONCLUSION

Reconstructive surgeries are common in RA, although patients diagnosed after 1985 are less likely to require joint surgery. These findings may reflect trends in medical disease management and have importance for health care resource utilization planning.

摘要

目的

描述在一个明确界定的、基于人群的类风湿关节炎(RA)患者队列中骨科手术(包括关节置换手术)的使用情况,并确定预测此类使用的特征。

方法

对1955年至1995年期间明尼苏达州罗切斯特市的RA发病病例进行回顾性病历审查。记录所有关节手术。

结果

在总共609例RA发病病例中,242例患者在随访期间接受了1次或更多次(每位患者最多20次)涉及关节的外科手术。总体而言,该RA队列每100人年随访中有7.4次手术;RA相关关节疾病在30年时的关节手术累积发病率为33.7%±标准误3.8%。女性、年轻、类风湿因子阳性且有类风湿结节的RA患者进行与疾病相关关节手术的风险增加。在对随访时间进行调整后,1985年后诊断为RA的患者接受RA关节手术的可能性显著降低(P<0.001)。接受全关节置换术的患者生存率与未接受者相似。

结论

重建手术在RA中很常见,尽管1985年后诊断的患者需要关节手术的可能性较小。这些发现可能反映了疾病管理的趋势,对医疗资源利用规划具有重要意义。

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