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[磁共振成像转移在多发性硬化症患者研究中的应用:文献综述与分析]

[The application of magnetic resonance imaging transfer to the study of multiple sclerosis patients: review and analysis of literature].

作者信息

Grimaud J, Zhou L Q, Zhu Y M

机构信息

Centre de Recherche et d'Applications en Traitement de l'Image et du Signal (CREATIS), UMR CNRS 5515, INSA-Lyon.

出版信息

Rev Neurol (Paris). 2002 Dec;158(12 Pt 1):1157-73.

Abstract

The purpose of this review of the literature is to analyze the contribution of magnetization transfer (MT) imaging techniques in understanding the various characteristics of multiple sclerosis. MT imaging allows contrast augmentation by use of magnetization transfer contrast. MT imaging allows lesion characterization by means of quantification of the degree of signal loss due to magnetization transfer contrast by a magnetization transfer ratio. It is used as an indicator of tissue destruction; in particular, to demyelination. Both applications of MT imaging in multiple sclerosis are studied in this review, as well as the methodological and technical limitations.

摘要

这篇文献综述的目的是分析磁化传递(MT)成像技术在理解多发性硬化症的各种特征方面的贡献。MT成像通过使用磁化传递对比来增强对比度。MT成像通过磁化传递比量化由于磁化传递对比导致的信号损失程度,从而实现病变特征的表征。它被用作组织破坏的指标,特别是用于脱髓鞘。本综述研究了MT成像在多发性硬化症中的这两种应用,以及方法学和技术上的局限性。

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