Seike Masahiro, Hirose Yasuaki, Ikeda Mitsunori, Kodama Hajime
Department of Dermatology, Kochi Medical School, Japan.
J Dermatol. 2003 Feb;30(2):132-4. doi: 10.1111/j.1346-8138.2003.tb00360.x.
A 61-year-old man presented with purple-red papules and plaques. These lesions on the nape and dorsal aspects of both hands displayed the histological findings characteristic of lichen planus. Riehl's melanosis, which is synonymous with pigmented contact dermatitis, was present on the forehead and bald scalp. Riehl's melanosis typically appears on the face and is induced by cosmetics. Causative factors in this case, however, remained undefined. The coexistence of lichen planus and Riehl's melanosis at separate sites in a single patient suggests that the two diseases represent manifestations of specific immune responses characteristic of lichenoid tissue reaction and situate in the same spectrum. The differences in the skin manifestations of lichen planus and Riehl's melanosis might depend on the severity of immune responses against intrinsic or extrinsic antigens. In addition, the skin manifestations of lichenoid tissue reaction might depend on the disposition of the lesion sites.
一名61岁男性出现紫红色丘疹和斑块。颈部及双手背部的这些皮损表现出扁平苔藓的组织学特征。前额及秃发头皮处存在Riehl黑变病,其与色素沉着性接触性皮炎同义。Riehl黑变病通常出现在面部,由化妆品诱发。然而,该病例的致病因素仍不明确。扁平苔藓和Riehl黑变病在同一患者的不同部位共存,提示这两种疾病代表了苔藓样组织反应特有的特异性免疫反应表现,且处于同一谱系。扁平苔藓和Riehl黑变病皮肤表现的差异可能取决于针对内源性或外源性抗原的免疫反应强度。此外,苔藓样组织反应的皮肤表现可能取决于皮损部位的分布。