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双向腔肺分流术中不同临时性体外分流技术的围手术期比较

Peri-operative comparison of different transient external shunt techniques in bidirectional cavo-pulmonary shunt.

作者信息

Tireli Emin, Basaran Murat, Kafali Eylul, Harmandar Bugra, Camci Emre, Dayioglu Enver, Onursal Ertan

机构信息

Department of Cardiovascular Surgery, Medical Faculty of Istanbul University, Istanbul, Turkey.

出版信息

Eur J Cardiothorac Surg. 2003 Apr;23(4):518-24. doi: 10.1016/s1010-7940(03)00012-5.

Abstract

OBJECTIVE

In patients with functional single ventricular physiology, the avoidance of cardiopulmonary bypass offers many advantages including earlier extubation, decreased necessity of inotropic support, improved hemodynamical status and reduced likelihood of post-operative prolonged pleural effusion. We believe that the bidirectional cavopulmonary anastomosis operations may be performed with transient external shunt techniques. The purpose of this prospective study is the peri- and post-operative comparison of different transient external shunt methods used in bidirectional cavopulmonary shunt operations.

METHODS

Between years 1997 and 2000, 30 patients have undergone bidirectional cavo-pulmonary shunt operation by using three different types of external shunt. The mean patient age was 13 months (range, 3 months-3 years). Previous operations had been performed in ten patients (33%). All patients were divided into three groups according to type of external shunt used. In group A (ten patients), the transient external shunt was constructed between superior vena cava and right atrium by uniting two standard venous cannulas with a Y-connector. In group B (ten patients), the external shunt was performed with a single short venous cannula constructed between superior vena cava and right atrium. In group C (ten patients), the external shunt was constructed between superior vena cava and left pulmonary artery by using a single short venous cannula. During operation, central venous pressure (CVP), arterial O(2) saturation and mean arterial blood pressure were recorded continuously.

RESULTS

All operations are completed without the establishment of cardiopulmonary bypass. Hospital mortality was 3.3%. One patient in group A died because of low cardiac output at the end of postoperative day 2. All patients were extubated within 4h. In groups A-C mean superior vena caval pressures were measured 28, 24 and 21 mmHg, respectively during superior vena cava-right pulmonary artery anastomosis. In both groups A and B patients, arterial O(2) saturation decreased to a minimum 53+/-2 and 53+/-2%, respectively during the operation. In the group C, minimum arterial O(2) saturation was measured 82+/-2%. Although mean arterial pressure decreased in all groups during clampage; in group C patients, this drop is not significant.

CONCLUSION

Based on the study presented here, bidirectional cavo-pulmonary anastomosis can be carried out by using different types of transient external shunt. The best hemodynamical condition and arterial O(2) levels were achieved with the shunt constructed between superior vena cava and left pulmonary artery.

摘要

目的

对于功能性单心室生理的患者,避免使用体外循环有诸多益处,包括更早拔管、减少使用血管活性药物支持的必要性、改善血流动力学状态以及降低术后长时间胸腔积液的可能性。我们认为双向腔肺吻合术可采用临时性体外分流技术进行。本前瞻性研究的目的是对双向腔肺分流手术中使用的不同临时性体外分流方法进行围手术期和术后比较。

方法

1997年至2000年间,30例患者采用三种不同类型的体外分流进行了双向腔肺分流手术。患者平均年龄为13个月(范围3个月至3岁)。10例患者(33%)曾接受过先前手术。所有患者根据所使用的体外分流类型分为三组。A组(10例患者),通过用Y形连接器连接两根标准静脉插管,在上腔静脉和右心房之间构建临时性体外分流。B组(10例患者),使用一根在上腔静脉和右心房之间构建的单一短静脉插管进行体外分流。C组(10例患者),使用一根单一短静脉插管在上腔静脉和左肺动脉之间构建体外分流。手术期间,持续记录中心静脉压(CVP)、动脉血氧饱和度和平均动脉血压。

结果

所有手术均在未建立体外循环的情况下完成。医院死亡率为3.3%。A组1例患者术后第2天末因心输出量低死亡。所有患者均在4小时内拔管。在A - C组中,在上腔静脉 - 右肺动脉吻合期间,平均上腔静脉压力分别测得为mmHg 28、24和21。在A组和B组患者中,手术期间动脉血氧饱和度分别降至最低53±2%和53±2%。在C组中,最低动脉血氧饱和度测得为82±2%。尽管在阻断期间所有组的平均动脉压均下降;但在C组患者中,这种下降不显著。

结论

基于本研究,双向腔肺吻合术可通过使用不同类型的临时性体外分流来进行。在上腔静脉和左肺动脉之间构建的分流实现了最佳的血流动力学状态和动脉血氧水平。

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