头低位卧床休息后动脉压力反射对交感缩血管神经活动及直立不耐受的控制

Arterial baroreflex control of sympathetic vasoconstrictor traffic and orthostatic intolerance after head-down bed rest.

作者信息

Kamiya A, Michikami D, Fu Q, Niimi Y, Iwase S, Mano T

机构信息

Dept. of Autonomic Neuroscience, Research Institute of Environmental Medicine, Nagoya University, Japan.

出版信息

J Gravit Physiol. 2000 Jul;7(2):P177-8.

PMID:12697515

Abstract

The purpose of the present study is to examine the changes in the arterial baroreflex control of muscle sympathetic nerve activity (MSNA) after head-down bed rest (HDBR), in relation to orthostatic hypotension after HDBR. Therefore, we performed 60 degrees head-up tilt (HUT) tests before and after 14 days of HDBR, with monitoring MSNA, heart rate and blood pressure. We calculated the gain of the arterial baroreflex control of MSNA, and compared the gains between the subjects who did (defined as the fainters) and those who did not (defined as the nonfainters) become presyncopal in HUT tests after HDBR.

摘要

本研究的目的是探讨头低位卧床休息（HDBR）后动脉压力反射对肌肉交感神经活动（MSNA）控制的变化，以及与HDBR后体位性低血压的关系。因此，我们在HDBR 14天前后进行了60度头高位倾斜（HUT）试验，同时监测MSNA、心率和血压。我们计算了动脉压力反射对MSNA控制的增益，并比较了HDBR后HUT试验中出现（定义为晕厥前期者）和未出现（定义为非晕厥前期者）晕厥前期症状的受试者之间的增益。