Turner Robert, Jones Terry
Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, UK.
Br Med Bull. 2003;65:3-20. doi: 10.1093/bmb/65.1.3.
In the last 20 years, a number of non-invasive spatial mapping techniques have been demonstrated to provide powerful insights into the operation of the brain during task performance. These are, in order of their emergence as robust technologies: positron emission tomography, source localization with EEG and MEG, and functional magnetic resonance imaging. The imaging neuroscience study areas represented in this volume use the first or last of these - PET and fMRI. The physical principles underlying both of these techniques are outlined, and the important assumptions and limitations are made explicit. The range of applications for each is briefly indicated.
在过去20年里,一些非侵入性空间映射技术已被证明能为任务执行过程中大脑的运作提供有力见解。按照其作为成熟技术出现的先后顺序,这些技术依次为:正电子发射断层扫描、利用脑电图(EEG)和脑磁图(MEG)进行源定位以及功能磁共振成像。本卷中所代表的成像神经科学研究领域使用了这些技术中的第一种或最后一种——正电子发射断层扫描和功能磁共振成像。概述了这两种技术背后的物理原理,并明确了重要的假设和局限性。简要介绍了每种技术的应用范围。