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福尼尔坏疽:重复手术清创分析

Fournier's gangrene: an analysis of repeated surgical debridement.

作者信息

Chawla Sam N, Gallop Christina, Mydlo Jack H

机构信息

Department of Urology, Temple University Medical Center, Philadelphia, PA 19140, USA.

出版信息

Eur Urol. 2003 May;43(5):572-5. doi: 10.1016/s0302-2838(03)00102-7.

Abstract

OBJECTIVES

We wanted to determine if there was a difference in outcome for those patients with Fournier's disease who underwent numerous debridements as opposed to only one initial debridement.

METHODS

The records of 19 patients with the diagnosis of Fournier's gangrene were reviewed retrospectively at our institution. Special attention was placed on demographic data, primary managing service, as well as wound cultures, and the number and timing of surgical debridements. Patients were also classified by a collection of variables at presentation and given a score named the Fournier's Severity Index. We utilised the Fournier's Severity Index (FSI) as developed by Laor et al. which included a number of vital sign data as well as laboratory values collected at admission in the emergency room.

RESULTS

The average FSI was 9.1 ranging from 0 to 15. The mean FSI of survivors was 8.6 versus 12.4 of non-survivors. The surgical management of this disease process was also critically examined. The average number of repeated debridements was 3.5 ranging from 1 to 8. Both the FSI and the number of debridements were attempted to be used to predict outcome. Outcome was measured in the variables length of stay (days) and survival. A regression analysis revealed the number of debridements to be positively related to the length of stay (LOS). This was the opposite as expected at the beginning of the study. Also FSI was not predictive of LOS.

CONCLUSIONS

Fournier's gangrene is a disease process with a wide variability in presentation. The FSI does give some indication about the likelihood of survival based on variables which can be recorded upon presentation. It also provides an efficient way to characterize the acuity of presentation and compare patients. While the repeated nature of debridements may be considered the accepted standard of care in these patients, this was not found to be predictive of outcome.

摘要

目的

我们想确定患有福尼尔氏病的患者,接受多次清创术与仅进行一次初始清创术相比,其治疗结果是否存在差异。

方法

我们机构对19例诊断为福尼尔氏坏疽的患者记录进行了回顾性分析。特别关注人口统计学数据、主要管理服务、伤口培养情况,以及手术清创的次数和时间。患者还根据就诊时的一系列变量进行分类,并给出一个名为福尼尔严重程度指数的评分。我们采用了劳尔等人制定的福尼尔严重程度指数(FSI),其中包括一些生命体征数据以及在急诊室入院时收集的实验室值。

结果

平均FSI为9.1,范围从0到15。幸存者的平均FSI为8.6,而非幸存者为12.4。我们还对该疾病过程的手术管理进行了严格审查。重复清创的平均次数为3.5次,范围从1到8次。我们尝试使用FSI和清创次数来预测治疗结果。治疗结果通过住院时间(天数)和生存情况等变量来衡量。回归分析显示清创次数与住院时间呈正相关。这与研究开始时的预期相反。此外,FSI不能预测住院时间。

结论

福尼尔氏坏疽是一种临床表现差异很大的疾病过程。FSI确实根据就诊时可记录的变量,对生存可能性给出了一些指示。它还提供了一种有效的方法来描述病情的严重程度并比较患者。虽然清创的重复性可能被认为是这些患者公认的护理标准,但未发现其能预测治疗结果。

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