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Challenges for clinical trials to treat progressive multifocal leukoencephalopathy.

作者信息

Clifford David B

机构信息

Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA.

出版信息

J Neurovirol. 2003;9 Suppl 1:68-72. doi: 10.1080/13550280390195324.

Abstract

Progressive multifocal leukoencephalopathy is a lethal complication of immunodeficiency for which no direct therapy has been achieved. The issues that have made this disease especially difficult to address are discussed, and an outline for development of future interventions is provided. A controlled trial of therapy utilizing an international group of trial groups is proposed.

摘要

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