Larrazet F, Philippe F, Folliguet T, Slama M, Meziane T, Bachet J, Laborde F, Dibie A
Institut mutualiste Montsouris, département de pathologie cardiaque, 42, bd Jourdan, 75674 Paris.
Arch Mal Coeur Vaiss. 2003 Mar;96(3):175-80.
Between September 1999 and June 2001, 591 patients required ad hoc coronary angioplasty. The authors compared the group of patients in whom the approach of first intent was radial (n = 328, 55%) with those in whom the femoral approach had been used (n = 263), in terms of immediate local (haematoma or thrombosis requiring surgical intervention or transfusion) and general complications (myocardial infarction, cerebrovascular accident), and major adverse cardiovascular events (infarction, angioplasty, bypass and death) at 1 year. The dose of ionising radiation during the procedures was also compared prospectively. The conversion rate from the radial (R) to the humeral or femoral (F) approach was 10%. The angioplasty, stenting, and stenting without dilatation failure rates were identical in the two groups (5% versus 5%, 0.6% versus 1.9%, 3% versus 4%, respectively). The average irradiation time was greater in the R group than in the F group (23 +/- 12 min vs 17 +/- 4 min, p < 0.001) as was the irradiation per surface unit (242 +/- 137 Gy.cm2 vs 185 +/- 117 Gy.cm2, p < 0.001). The immediate complication rate was comparable in the two groups (2.5% in group R vs 3.6% in group F) as was the major adverse cardiovascular event rate at 1 year (13% in both groups). The authors observed the same rate of immediate complications and late adverse cardiac events in patients undergoing coronary angioplasty followed by immediate angioplasty by the radial or femoral approaches with an acceptable conversion rate from the radial to the femoral approach. The procedures by the radial approach seem to be associated with a greater time and dosage of ionising radiation.
1999年9月至2001年6月期间,591例患者需要进行临时冠状动脉血管成形术。作者比较了首次意向采用桡动脉入路的患者组(n = 328,55%)和采用股动脉入路的患者组(n = 263),比较内容包括即刻局部并发症(需要手术干预或输血的血肿或血栓形成)和全身并发症(心肌梗死、脑血管意外),以及1年时的主要不良心血管事件(梗死、血管成形术、搭桥手术和死亡)。还对手术过程中的电离辐射剂量进行了前瞻性比较。从桡动脉(R)入路转换为肱动脉或股动脉(F)入路的转换率为10%。两组的血管成形术、支架置入术以及未扩张的支架置入术失败率相同(分别为5%对5%、0.6%对1.9%、3%对4%)。R组的平均照射时间比F组更长(23±12分钟对17±4分钟,p<0.001),每单位面积的照射量也是如此(242±137 Gy.cm²对185±117 Gy.cm²,p<0.001)。两组的即刻并发症发生率相当(R组为2.5%,F组为3.6%),1年时的主要不良心血管事件发生率也相当(两组均为13%)。作者观察到,采用桡动脉或股动脉入路进行冠状动脉血管成形术并即刻血管成形术的患者,其即刻并发症发生率和晚期不良心脏事件发生率相同,且桡动脉至股动脉入路的转换率可接受。桡动脉入路的手术似乎与更长的电离辐射时间和剂量相关。