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[间质性肺疾病]

[Interstitial lung diseases].

作者信息

Mazzoccoli Gianluigi, Carughi Stefano, De Cata Angelo, Giuliani Antonio, Masciale Nunzia, La Viola Marco, Puzzolante Felice, Balzanelli Mario

机构信息

Divisione di Medicina Interna, IRCCS Casa Sollievo della Sofferenza, Opera di Padre Pio da Pietrelcina, San Giovanni Rotondo.

出版信息

Recenti Prog Med. 2003 May;94(5):227-37.

Abstract

Interstitial lung diseases (ILD) are an heterogeneous group of inflammatory diseases characterized by an anatomical distortion of peripheral airways and interstitium, determined by a first stage of alveolitis and a following stage of fibrosis. Natural history of several ILD is characterized by slow and progressive destruction of alveolar-capillary functional units, often with respiratory failure and death. For their smoldering evolution and not specificity of symptoms (exertional dyspnea and cough) ILD may remain not diagnosed and not treated for a long time.

摘要

间质性肺疾病(ILD)是一组异质性炎症性疾病,其特征是外周气道和间质的解剖结构扭曲,由肺泡炎的第一阶段和随后的纤维化阶段所决定。几种ILD的自然史特征是肺泡-毛细血管功能单位的缓慢进行性破坏,常伴有呼吸衰竭和死亡。由于其隐匿性进展以及症状(劳力性呼吸困难和咳嗽)缺乏特异性,ILD可能长期未被诊断和治疗。

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