Mattson Richard H
Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520, U.S.A.
Epilepsia. 2003;44 Suppl 2:2-6. doi: 10.1046/j.1528-1157.44.s.2.3.x.
The idiopathic generalized epilepsies (IGEs) are an underemphasized topic. Two reasons for this relative lack of attention are that these epilepsies tend to be more easily controlled than the symptomatic partial and generalized epilepsies, and they are not as common. Because IGE usually arises in childhood or adolescence, these epilepsies may be thought of as a pediatric problem. However, a large number of patients continue to have seizures in adult life. Many exciting developments in understanding the pathophysiology, genetic etiology, and expanded treatment options warrant a reexamination of this important group of the epilepsies. This article reviews the more common IGE syndromes and associated seizure types as the first step in identifying the recent advances in our knowledge of these syndromes.
特发性全身性癫痫(IGEs)是一个未得到充分重视的话题。相对缺乏关注的两个原因是,这些癫痫往往比症状性部分性和全身性癫痫更容易控制,而且它们并不常见。由于IGE通常在儿童期或青少年期发病,这些癫痫可能被认为是儿科问题。然而,大量患者在成年后仍会发作。在理解病理生理学、遗传病因以及扩展治疗选择方面有许多令人兴奋的进展,这使得有必要重新审视这一重要的癫痫群体。本文回顾了更常见的IGE综合征及相关发作类型,作为识别我们对这些综合征认识的最新进展的第一步。