Baca Pilar, Junco Pilar, Bravo Manuel, Baca Adela P, Muñoz M José
Department of Preventive Dentistry, School of Dentistry, University of Granada, Granada, Spain.
Community Dent Oral Epidemiol. 2003 Jun;31(3):179-83. doi: 10.1034/j.1600-0528.2003.00034.x.
To determine whether the cessation for 3 years of a 24-month program of chlorhexidine-thymol varnish applications would affect caries incidence in the first permanent molars of a population of schoolchildren of middle and lower-middle socioeconomic level.
Two groups of 6-7-year-old schoolchildren, randomized by school-class, were followed up in a clinical trial. One group received applications of chlorhexidine-thymol varnish every 3 months and the other group acted as controls. The program ended after 24 months and its effects were evaluated. Three years later, 55.5% of the schoolchildren were re-examined and the caries increments were documented.
At the end of the 24-month program, the treated children had significantly fewer decayed and filled surfaces in permanent molars (lower DFS index) versus the controls. At 3 years after the discontinuation of the program, this difference had disappeared; there were no differences in the incidence of decayed, missing and filled surfaces (DMFS) index in permanent molars between the treated children and the controls.
The cessation for 3 years of a 3-month program of chlorhexidine-thymol varnish applications resulted in a nonsignificant increase in the prevalence of dental caries in the permanent first molar.
确定为期24个月的洗必泰-百里酚涂剂应用计划停止3年是否会影响社会经济水平处于中低等的学龄儿童群体第一恒磨牙的龋病发病率。
在一项临床试验中，按学校班级将两组6-7岁学龄儿童随机分组并进行随访。一组每3个月接受一次洗必泰-百里酚涂剂，另一组作为对照组。该计划在24个月后结束并评估其效果。三年后，对55.5%的学龄儿童进行复查并记录龋病增量。
在24个月计划结束时，与对照组相比，接受治疗的儿童恒磨牙中龋坏和充填牙面显著更少（DFS指数更低）。在该计划停止3年后该差异消失；接受治疗的儿童与对照组在恒磨牙龋失补牙面（DMFS）指数的发病率上无差异。
为期24个月的洗必泰-百里酚涂剂应用计划停止3年导致第一恒磨牙龋病患病率非显著性增加。
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