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急性胸主动脉综合征患者的血管内支架植入术。

Endovascular stent graft placement in patients with acute thoracic aortic syndromes.

作者信息

Grabenwoger Martin, Fleck Tatjana, Czerny Martin, Hutschala Doris, Ehrlich Marek, Schoder Maria, Lammer Johannes, Wolner Ernst

机构信息

Department of Cardio-thoracic Surgery, University of Vienna, Austria.

出版信息

Eur J Cardiothorac Surg. 2003 May;23(5):788-93; discussion 793. doi: 10.1016/s1010-7940(03)00075-7.

Abstract

OBJECTIVE

In the present study, the effectiveness of endovascular stent grafts (ESG) in the treatment of acute aortic complications, such as acute dissection type B, penetrating ulcer and traumatic aortic rupture is evaluated.

PATIENTS AND METHODS

From June 1997 to February 2002, 66 patients were treated with ESG. Out of this cohort, 19 patients (28.8%) were subjected to stent grafting due to acute aortic syndromes. Acute dissection type B was present in 11 patients (16.6%), a penetrating ulcer was diagnosed in six patients (9%) and in 2 patients (3%) a traumatic aneurysm was the indication for operation. There were 16 male and three female patients with a mean age of 60 years (20-85 years). Excluder stent grafts (Gore) were used in 15 patients, the Talent device (Medtronic) was implanted in four patients.

RESULTS

Stent graft placement was technically successful in all patients. Hospital mortality was 0%. Paraparesis occurred in one patient (5.2%), which could be managed successfully without remaining neurological deficit after installation of cerebrospinal fluid drainage for 72h. In another patient, overstenting of the left subclavian artery caused ischemia of the left arm and left subclavian to carotid artery bypass had to be performed. ICU-stay ranged from 1 to 6 days (mean 2.4 days) and the patients could be discharged after an average hospital stay of 8 days. In the follow-up period, one patient died due to myocardial infarction and one patient had to be re-operated due to contained rupture of the thoracic aorta caused by an endoleak.

CONCLUSIONS

The study suggests that endovascular stent grafting is an excellent and effective treatment modality for the acute aortic accident, which can be recommended for high-risk patients too. However, close follow-up examination is indicated and long-term results have to be awaited to evaluate the real effectiveness of this method.

摘要

目的

在本研究中,评估血管内支架移植物(ESG)治疗急性主动脉并发症(如B型急性夹层、穿透性溃疡和创伤性主动脉破裂)的有效性。

患者与方法

1997年6月至2002年2月,66例患者接受了ESG治疗。在该队列中,19例患者(28.8%)因急性主动脉综合征接受了支架植入术。11例患者(16.6%)为B型急性夹层,6例患者(9%)诊断为穿透性溃疡,2例患者(3%)因创伤性动脉瘤而接受手术。有16例男性和3例女性患者,平均年龄60岁(20 - 85岁)。15例患者使用了Excluder支架移植物(戈尔公司),4例患者植入了Talent装置(美敦力公司)。

结果

所有患者的支架植入在技术上均获成功。医院死亡率为0%。1例患者(5.2%)发生了下肢轻瘫,在安装脑脊液引流72小时后成功处理,未遗留神经功能缺损。另一例患者,左锁骨下动脉过度支架植入导致左臂缺血,不得不进行左锁骨下动脉至颈动脉旁路移植术。重症监护病房住院时间为1至6天(平均2.4天),患者平均住院8天后可出院。在随访期,1例患者死于心肌梗死,1例患者因内漏导致胸主动脉局限性破裂而不得不再次手术。

结论

该研究表明,血管内支架植入术是治疗急性主动脉急症的一种出色且有效的治疗方式,也可推荐用于高危患者。然而,需要进行密切的随访检查,且必须等待长期结果来评估该方法的实际有效性。

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