[正角化牙源性囊肿：一项临床病理及免疫细胞化学研究]
[Orthokeratinized odontogenic cyst: a clinicopathological and immunocytochemical study].
作者信息
Li Tie-jun, Luo Hai-yan, Yu Shi-feng
机构信息
Department of Pathology, Peking University School of Stomatology, Beijing 100081, China.
出版信息
Zhonghua Kou Qiang Yi Xue Za Zhi. 2003 Jan;38(1):49-51.
OBJECTIVE
To investigate the clinicopathological features and behavior of a group of jaw cysts with a solely orthokeratinized lining epithelium.
METHODS
20 cases of this cyst type were reported under the term of orthokeratinized odontogenic cyst (OOC) and their clinical, histological and immunocytochemical features were compared with that of odontogenic keratocyst (OKC).
RESULTS
The cysts of the present series were all solitary lesions, occurred mostly in young male patients, and showed a predilection for the posterior mandible areas. Follow-up of 15 patients revealed no recurrence following enucleation. Histological and immunocytochemical studies indicated that OOC epithelium lacked the typical features of OKC and appeared to show a lower proliferative activity.
CONCLUSION
These findings suggest that OOC is clinicopathologically distinctive from OKC and may thus constitute its own clinical entity.
目的
研究一组仅具有正角化衬里上皮的颌骨囊肿的临床病理特征及生物学行为。
方法
报道20例诊断为正角化牙源性囊肿（OOC）的此类囊肿病例，并将其临床、组织学及免疫细胞化学特征与牙源性角化囊肿（OKC）进行比较。
结果
本系列囊肿均为孤立性病变，多见于年轻男性患者，好发于下颌骨后部区域。15例患者随访显示摘除术后无复发。组织学及免疫细胞化学研究表明，OOC上皮缺乏OKC的典型特征，增殖活性似乎较低。
结论
这些发现提示OOC在临床病理上有别于OKC，可能构成其自身的临床实体。
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