Lundbäck B, Gulsvik A, Albers M, Bakke P, Rönmark E, van den Boom G, Brøgger J, Larsson L G, Welle I, van Weel C, Omenaas E
Unit for Lung and Allergy Research, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Eur Respir J Suppl. 2003 May;40:3s-9s. doi: 10.1183/09031936.03.00403103.
The burdens of chronic obstructive airway diseases among the elderly in Europe, and worldwide, are increasing. Although asthma is common in all ages, the main airway disease affecting the elderly is chronic obstructive pulmonary disease (COPD). The aim of this paper is to review the prevalence and incidence of COPD on the basis of population studies. As the prevalence estimates of asthma are probably well known, only the incidence and remission of asthma will be discussed. The underdiagnosis of obstructive airway diseases is huge. A Dutch programme for early detection of obstructive airway disease among the elderly has, thus, been included in the presentation. A prerequisite for fighting COPD is to acquire data on illnesses and death. COPD has only recently been defined by cut-off points of spirometric outcomes, which is why measures of the prevalence of COPD have been distorted by use of a large number of different diagnostic terms and lung function criteria. The prevalence of clinically-relevant COPD has been estimated in several community studies to 4-6% in adult population samples, with a considerable increase by age, particularly among smokers. The incidence of COPD not only increases heavily with age and smoking, but also occupational exposure to dust, gas and damp. Precise estimates of the incidence of COPD or spirometric airflow limitation are not available. Demographic changes will result in a further substantial increase of chronic obstructive airway disorders, mainly chronic obstructive pulmonary disease, among the elderly. The increasing burden of chronic obstructive pulmonary disease has to come to the awareness of the public, governments, health authorities, and industry.
在欧洲乃至全球,老年人慢性阻塞性气道疾病的负担正在增加。虽然哮喘在各年龄段都很常见,但影响老年人的主要气道疾病是慢性阻塞性肺疾病(COPD)。本文旨在基于人群研究回顾COPD的患病率和发病率。由于哮喘的患病率估计可能广为人知,因此仅讨论哮喘的发病率和缓解情况。阻塞性气道疾病的漏诊情况非常严重。因此,荷兰一项针对老年人阻塞性气道疾病早期检测的计划也被纳入了本文介绍内容。对抗COPD的一个先决条件是获取疾病和死亡数据。COPD直到最近才通过肺功能测定结果的临界点来定义,这就是为什么COPD患病率的测量因使用大量不同的诊断术语和肺功能标准而受到扭曲。在一些社区研究中,成人样本中具有临床相关性的COPD患病率估计为4% - 6%,且随年龄显著增加,尤其是吸烟者。COPD的发病率不仅随年龄和吸烟大幅增加,还与职业性接触粉尘、气体和潮湿环境有关。目前尚无COPD或肺功能测定气流受限发病率的精确估计。人口结构变化将导致老年人慢性阻塞性气道疾病,主要是慢性阻塞性肺疾病,进一步大幅增加。慢性阻塞性肺疾病日益加重的负担必须引起公众、政府、卫生当局和行业的关注。