Schober B, Hunt J A
Can Med Assoc J. 1976 Jul 3;115(1):29-35.
Uptake of radioactive iodine by the thyroid gland after oral administration of 75 muCi was determined in 1971-72 in 60 euthyroid female volunteers from the North Shore of Vancouver. Values were as low as 3% at 4 hours and 7% at 24 hours in subjects otherwise proven to be euthyroid. The highest values found were 13 and 26% at 4 and 24 hours. The effective thyroxine ratios were all within the accepted normal range. However, more than half of the volunteers showed some enlargement of the thyroid gland. These results suggest an increased iodine pool in the subjects, the likley source being iodine in mild, dairy products and erythrosine, a colouring agent in foods and pharmaceutical products. Potassium iodate, used sometimes in bread baking, contributed little to this pool in our sample. Subjects were, on the average, 9 to 25% heavier than their peers 20 years ago.
1971年至1972年期间,对来自温哥华北岸的60名甲状腺功能正常的女性志愿者进行了口服75微居里放射性碘后甲状腺摄取情况的测定。在其他方面经证实甲状腺功能正常的受试者中,4小时时摄取值低至3%,24小时时为7%。所发现的最高值在4小时和24小时时分别为13%和26%。有效甲状腺素比率均在公认的正常范围内。然而,超过一半的志愿者甲状腺出现了一定程度的肿大。这些结果表明受试者体内碘储备增加,可能的来源是轻度碘、乳制品和赤藓红(食品和药品中的一种着色剂)。面包烘焙中有时使用的碘酸钾在我们的样本中对这一储备贡献不大。受试者的平均体重比20年前的同龄人重9%至25%。