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青少年闭角型青光眼

Angle-closure glaucoma in teenagers.

作者信息

Badlani Vandana K, Quinones Richard, Wilensky Jacob T, Hawkins Anjali, Edward Deepak P

机构信息

Department of Ophthalmology and Visual Sciences, 1855 West Taylor, Chicago, IL, USA.

出版信息

J Glaucoma. 2003 Jun;12(3):198-203. doi: 10.1097/00061198-200306000-00003.

DOI:10.1097/00061198-200306000-00003
PMID:12782835
Abstract

OBJECTIVE

To report the occurrence of angle-closure glaucoma in 2 teenagers.

DESIGN

Observational case reports, review of literature.

METHODS

Review of case histories, examinations, biometries, visual fields, and ultrasound biomicroscopy findings in 2 teenagers with angle-closure glaucoma.

MAIN OUTCOME MEASURES

Intraocular pressure, gonioscopy, Humphrey 24-2 visual field (SITA Standard), and ultrasound biomicroscopy.

RESULTS

The first case involved a 15-year-old white male who presented with an intraocular pressure of 60 mm Hg in the right eye and 24 mm Hg in the left eye and 360-degree appositional closure in both eyes. Ultrasound biomicroscopy revealed prominent bilateral ciliary pigment epithelial cysts pushing the iris anteriorly towards the angle. The second case involved a 14-year-old white male with a strong family history of primary angle-closure glaucoma. The patient had pupillary block and an intraocular pressure of 24 mm Hg in the right eye and 40 mm Hg in the left eye on routine eye examination. Gonioscopy and ultrasound biomicroscopy revealed appositional closure of the angle in all 4 quadrants bilaterally.

CONCLUSION

Primary angle-closure glaucoma is uncommon in younger individuals. Therefore, the finding of angle-closure glaucoma in a young individual should alert the physician to the possibility of a secondary cause of angle closure, such as iris pigment epithelial cysts. In addition, special attention to family history is important as the configuration of an occludable anterior chamber angle may, in some instances, be inherited.

摘要

目的

报告2例青少年闭角型青光眼的发病情况。

设计

观察性病例报告,文献回顾。

方法

回顾2例青少年闭角型青光眼患者的病史、检查、生物测量、视野及超声生物显微镜检查结果。

主要观察指标

眼压、前房角镜检查、Humphrey 24-2视野(SITA标准)及超声生物显微镜检查。

结果

第一例为一名15岁白人男性,右眼眼压60 mmHg,左眼眼压24 mmHg,双眼均为360度贴附性房角关闭。超声生物显微镜检查显示双侧睫状体色素上皮囊肿突出,将虹膜向前推向房角。第二例为一名14岁白人男性,有原发性闭角型青光眼的家族史。该患者在常规眼科检查中发现瞳孔阻滞,右眼眼压24 mmHg,左眼眼压40 mmHg。前房角镜检查和超声生物显微镜检查显示双侧4个象限均有房角贴附性关闭。

结论

原发性闭角型青光眼在年轻人中并不常见。因此,在年轻个体中发现闭角型青光眼应提醒医生注意房角关闭的继发原因,如虹膜色素上皮囊肿。此外,由于在某些情况下,可关闭的前房角结构可能是遗传的,因此特别关注家族史很重要。

相似文献

1
Angle-closure glaucoma in teenagers.青少年闭角型青光眼
J Glaucoma. 2003 Jun;12(3):198-203. doi: 10.1097/00061198-200306000-00003.
2
Case report: imaging and treatment of ophthalmic manifestations in oculodentodigital dysplasia.病例报告:眼牙指发育异常的眼部表现的影像学及治疗
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Laser iridocystotomy for bilateral acute angle-closure glaucoma secondary to iris cysts.激光虹膜囊肿造瘘术治疗继发于虹膜囊肿的双侧急性闭角型青光眼。
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Glaucoma due to ciliary body cysts and pseudoplateau iris: a systematic review of the literature.睫状体囊肿和假性房角退缩性青光眼:文献系统综述
Arq Bras Oftalmol. 2018 Jun;81(3):254-261. doi: 10.5935/0004-2749.20180051.
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Bilateral Multiple Ciliary Body Cysts with Angle-Closure Glaucoma in an 18-Year-Old Patient.18 岁患者双侧睫状体多发囊肿伴闭角型青光眼。
Middle East Afr J Ophthalmol. 2023 Feb 24;29(2):100-102. doi: 10.4103/meajo.meajo_185_22. eCollection 2022 Apr-Jun.
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Angle closure glaucoma due to iris and ciliary body cysts.虹膜和睫状体囊肿所致闭角型青光眼
Aust N Z J Ophthalmol. 1989 Aug;17(3):317-9. doi: 10.1111/j.1442-9071.1989.tb00541.x.
7
Ultrasound biomicroscopy evaluation of angle closure in a patient with multiple and bilateral iridociliary cysts.超声生物显微镜对一名患有多发双侧虹膜睫状体囊肿患者房角关闭情况的评估
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Arch Ophthalmol. 1996 Jun;114(6):666-8. doi: 10.1001/archopht.1996.01100130658004.
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Chronic angle closure glaucoma secondary to frail zonular fibres and spherophakia.继发于脆弱的晶状体悬韧带和球形晶状体的慢性闭角型青光眼。
Acta Ophthalmol Scand. 2003 Oct;81(5):533-5. doi: 10.1034/j.1600-0420.2003.00129.x.
10
Ultrasound biomicroscopy of ciliary body cysts.睫状体囊肿的超声生物显微镜检查
Am J Ophthalmol. 1999 Aug;128(2):259-60.

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Eye (Lond). 2025 Jul 18. doi: 10.1038/s41433-025-03884-1.
2
The ocular biometry characteristics of young patients with primary angle-closure glaucoma.原发性闭角型青光眼年轻患者的眼部生物测量特征。
BMC Ophthalmol. 2022 Apr 2;22(1):150. doi: 10.1186/s12886-022-02374-2.
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Ocular Biometry of Primary Angle-Closure Disease in Younger Patients.年轻患者原发性闭角型青光眼的眼生物测量
Front Med (Lausanne). 2021 Nov 3;8:772578. doi: 10.3389/fmed.2021.772578. eCollection 2021.
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Effect of primary iris and ciliary body cyst on anterior chamber angle in patients with shallow anterior chamber.原发性虹膜睫状体囊肿对浅前房患者前房角的影响。
J Zhejiang Univ Sci B. 2012 Sep;13(9):723-30. doi: 10.1631/jzus.B1200124.
5
Anterior segment imaging for glaucoma: OCT or UBM?青光眼的眼前节成像:光学相干断层扫描(OCT)还是超声生物显微镜(UBM)?
Br J Ophthalmol. 2007 Nov;91(11):1420-1. doi: 10.1136/bjo.2007.121038.