Suppr超能文献

[超声心动图在缺血性二尖瓣反流检测及预后评估中的作用]

[Role of echocardiography in the detection and prognosis of ischemic mitral regurgitation].

作者信息

Messika-Zeitoun David, Fung Yiu Siu, Grigioni Francesco, Enriquez-Sarano Maurice

机构信息

Division of Cardiovascular Diseases. Mayo Clinic. Rochester. Minnesota. USA.

出版信息

Rev Esp Cardiol. 2003 Jun;56(6):529-34. doi: 10.1016/s0300-8932(03)76912-7.

Abstract

Ischemic mitral regurgitation (IMR) is mitral regurgitation (MR) due to complications of coronary artery disease and not fortuitously associated with it. Acute MR secondary to ruptured papillary muscle after myocardial infarction is rare and often fatal. We focus on functional MR, much more common, which occurs without any intrinsic valve disease. It was often underrated because of low murmur intensity but with the use of echocardiography this complication is observed between 15%-20% after a myocardial infarction. Recent advances in noninvasive Doppler echocardiography allow accurate assessment of regurgitant volume and effective regurgitant orifice and thus provide the tools to reliably evaluate the prognosis and mechanisms of IMR. IMR presence is associated with excess mortality. The mortality risk is directly related to the degree of regurgitation and a regurgitant volume > or = 30 ml or an effective regurgitant orifice > or = 20 mm2; define a high-risk group. Presence and degree of the regurgitation are related to local left ventricular remodeling. The apical and posterior displacement of papillary muscles leads to excess valvular tenting which in turn, in association with loss of systolic annular contraction, determines the severity of the regurgitation. In current clinical practice, IMR is mainly corrected by ring annuloplasty. However, this technique does not correct local alterations of left ventricular remodeling and its benefits on long-term outcome remains to be demonstrated.

摘要

缺血性二尖瓣反流(IMR)是指由于冠状动脉疾病并发症引起的二尖瓣反流(MR),而非偶然与之相关。心肌梗死后继发乳头肌破裂导致的急性MR较为罕见,且常是致命的。我们关注的是功能性MR,这种情况更为常见,它在没有任何内在瓣膜疾病的情况下发生。由于杂音强度较低,它常常被低估,但随着超声心动图的应用,在心肌梗死后,这种并发症的检出率为15%-20%。无创多普勒超声心动图的最新进展使得能够准确评估反流容积和有效反流口面积,从而为可靠地评估IMR的预后和机制提供了工具。IMR的存在与死亡率增加相关。死亡风险与反流程度直接相关,反流容积≥30 ml或有效反流口面积≥20 mm²定义为高危组。反流的存在和程度与局部左心室重构有关。乳头肌的顶端和向后移位导致瓣膜过度膨出,进而与收缩期瓣环收缩丧失一起决定了反流的严重程度。在当前临床实践中,IMR主要通过环缩成形术进行纠正。然而,该技术并不能纠正左心室重构的局部改变,其对长期预后的益处仍有待证实。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验