Clarke P, Gray A, Legood R, Briggs A, Holman R
Health Economics Research Centre and Diabetes Trials Unit, University of Oxford, Oxford, UK.
Diabet Med. 2003 Jun;20(6):442-50. doi: 10.1046/j.1464-5491.2003.00972.x.
To develop a model for estimating the immediate and long-term healthcare costs associated with seven diabetes-related complications in patients with Type 2 diabetes participating in the UK Prospective Diabetes Study (UKPDS).
The costs associated with some major complications were estimated using data on 5102 UKPDS patients (mean age 52.4 years at diagnosis). In-patient and out-patient costs were estimated using multiple regression analysis based on costs calculated from the length of admission multiplied by the average specialty cost and a survey of 3488 UKPDS patients' healthcare usage conducted in 1996-1997.
Using the model, the estimate of the cost of first complications were as follows: amputation pound 8459 (95% confidence interval pound 5295, pound 13 200); non-fatal myocardial infarction pound 4070 ( pound 3580, pound 4722); fatal myocardial infarction pound 1152 ( pound 941, pound 1396); fatal stroke pound 3383 ( pound 1935, pound 5431); non-fatal stroke pound 2367 ( pound 1599, pound 3274); ischaemic heart disease pound 1959 ( pound 1467, pound 2541); heart failure pound 2221 ( pound 1690, pound 2896); cataract extraction pound 1553 ( pound 1320, pound 1855); and blindness in one eye pound 872 ( pound 526, pound 1299). The annual average in-patient cost of events in subsequent years ranged from pound 631 ( pound 403, pound 896) for heart failure to pound 105 ( pound 80, pound 142) for cataract extraction. Non-in-patient costs for macrovascular complications were pound 315 ( pound 247, pound 394) and for microvascular complications were pound 273 ( pound 215, pound 343) in the year of the event. In each subsequent year the costs were, respectively, pound 258 ( pound 228, pound 297) and pound 204 ( pound 181, pound 255).
These results provide estimates of the immediate and long-term healthcare costs associated with seven diabetes-related complications.
建立一个模型，用于估算参与英国前瞻性糖尿病研究（UKPDS）的2型糖尿病患者七种糖尿病相关并发症的直接和长期医疗费用。
利用5102例UKPDS患者（诊断时平均年龄52.4岁）的数据估算一些主要并发症的费用。住院和门诊费用采用多元回归分析估算，该分析基于住院时间乘以平均专科费用计算得出的费用以及1996 - 1997年对3488例UKPDS患者医疗使用情况的调查。
使用该模型，首次并发症费用的估算如下：截肢8459英镑（95%置信区间5295英镑，13200英镑）；非致命性心肌梗死4070英镑（3580英镑，4722英镑）；致命性心肌梗死1152英镑（941英镑，1396英镑）；致命性中风3383英镑（1935英镑，5431英镑）；非致命性中风2367英镑（1599英镑，3274英镑）；缺血性心脏病1959英镑（1467英镑，2541英镑）；心力衰竭2221英镑（1690英镑，2896英镑）；白内障摘除1553英镑（1320英镑，1855英镑）；单眼失明872英镑（526英镑，1299英镑）。后续年份事件的年平均住院费用从心力衰竭的631英镑（403英镑，896英镑）到白内障摘除的105英镑（80英镑，142英镑）不等。大血管并发症事件当年的非住院费用为315英镑（247英镑，394英镑），微血管并发症为273英镑（215英镑，343英镑）。在随后的每一年，费用分别为258英镑（228英镑，297英镑）和204英镑（181英镑，255英镑）。
这些结果提供了与七种糖尿病相关并发症相关的直接和长期医疗费用的估算。
Zotero 插件