Buchanan Glenn S, Rodgers George M, Ware Branch D
Department of Internal Medicine, University of Utah Health Sciences Center, 30 North 1900 East Medical Drive, Salt Lake City, UT 84132, USA.
Best Pract Res Clin Obstet Gynaecol. 2003 Jun;17(3):397-411. doi: 10.1016/s1521-6934(03)00010-5.
It is now possible to identify a predisposing thrombophilic condition for venous thrombosis in well over half of the cases. Certain thrombophilia diagnoses have a major impact on anticoagulant therapy, and hence it is incumbent upon physicians to understand how to diagnose and manage these conditions. This chapter covers the genetics and epidemiology of the inherited thrombophilias and provides a useful, common-sense approach to the laboratory evaluation of a patient with venous thrombosis.
现在,在超过半数的病例中都有可能识别出导致静脉血栓形成的易栓症状态。某些易栓症诊断对抗凝治疗有重大影响,因此医生有责任了解如何诊断和处理这些病症。本章涵盖遗传性易栓症的遗传学和流行病学,并提供一种实用、基于常识的方法来对静脉血栓形成患者进行实验室评估。