噬菌体λ阻遏物对Rex排除表型的等位基因调控
Bacteriophage lambda repressor allelic modulation of the Rex exclusion phenotype.
作者信息
Slavcev Roderick A, Bull Harold J, Hayes Sidney
机构信息
Department of Microbiology and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
出版信息
Can J Microbiol. 2003 Mar;49(3):225-9. doi: 10.1139/w03-021.
The sensitivity of delta red-gam delta ren mutants of bacteriophage lambda to Rex exclusion by lambda rexA+ rexB+ lysogens is modulated by the prophage cI repressor allele. We show the following: (i) lambda spi156 delta nin5 forms plaques on a cI+-rexA+-rexB+ lysogen with 10(5)-fold higher efficiency than on cI[Ts]-rexA+-rexB+ derivatives. (ii) The cI[Ts]857 allele augmentation of Rex exclusion is recessive to cI+. (iii) The cI857-mediated increase in Rex exclusion activity involves the participation of a genetic element mapping outside of cI-rexA-rexB.
噬菌体λ的δred - gam δren突变体对λ rexA + rexB +溶原菌的Rex排斥的敏感性受原噬菌体cI阻遏物等位基因的调节。我们展示了以下内容：(i) λ spi156 δnin5在cI + - rexA + - rexB +溶原菌上形成噬菌斑的效率比在cI[Ts] - rexA + - rexB +衍生物上高10^5倍。(ii) Rex排斥的cI[Ts]857等位基因增强相对于cI +是隐性的。(iii) cI857介导的Rex排斥活性增加涉及一个位于cI - rexA - rexB之外的遗传元件的参与。
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