Okuda Darin, Flaster Murray, Frey James, Sivakumar Kumaraswamy
Division of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
Neurology. 2003 Jun 10;60(11):1825-6. doi: 10.1212/01.wnl.0000068334.04500.08.
IV immunoglobulin therapy can lead to vascular events through increased serum viscosity and possibly other mechanisms. The authors describe the successful use of tissue plasminogen activator in three of four patients who developed cerebral and peripheral arterial thrombosis after treatment with IV immunoglobulin.