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滑膜肉瘤——伴有脑出血的不寻常表现。

Synovial sarcoma--unusual presentation with cerebral hemorrhage.

作者信息

Przkora Rene, Vogel Peter, Ullrich Odo W, Knüchel Ruth, Jauch Karl W, Bolder Ulrich

机构信息

Department of Surgery, University of Regensburg Medical Center, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany.

出版信息

Arch Orthop Trauma Surg. 2003 Sep;123(7):376-8. doi: 10.1007/s00402-003-0534-8. Epub 2003 Jun 12.

Abstract

INTRODUCTION

Soft-tissue sarcomas account for 1% of all malignancies in adults. Typical symptoms comprise a growing and painless mass. Occasionally, the diagnosis is facilitated by secondaries.

MATERIALS AND METHODS

Here we report the first case presented with intracranial hemorrhage caused by a metastasis of a previously unknown synovial sarcoma. The 74-year-old female patient was under anticoagulation for recurrent thrombosis of the right popliteal vein due to compression by the sarcoma, misdiagnosed as Baker's cyst. The brain metastasis was resected, and after an incisional biopsy of the suspected tumor, which confirmed the diagnosis of a synovial sarcoma, an above knee amputation was performed because of the invasion of the neurovascular structures in the popliteal fossa.

RESULTS

The patient died 11 months after the initial event from pulmonary and further brain metastases.

CONCLUSION

Brain metastases are seldom the primary factor in the management of advanced synovial sarcoma. Initially, the primary tumor was thought to be a benign cyst; we therefore recommend a biopsy/excision of lesions greater than 5 cm in size and with growth tendency to allow appropriate treatment.

摘要

引言

软组织肉瘤占成人所有恶性肿瘤的1%。典型症状包括逐渐增大且无痛的肿块。偶尔,转移灶有助于诊断。

材料与方法

在此我们报告首例因先前未知的滑膜肉瘤转移导致颅内出血的病例。这位74岁的女性患者因肉瘤压迫右腘静脉反复血栓形成而接受抗凝治疗,最初被误诊为贝克囊肿。切除了脑转移瘤,在对疑似肿瘤进行切开活检确诊为滑膜肉瘤后,由于腘窝神经血管结构受侵犯,进行了膝上截肢术。

结果

患者在初次发病11个月后死于肺转移和进一步的脑转移。

结论

脑转移很少是晚期滑膜肉瘤治疗的主要因素。最初,原发肿瘤被认为是良性囊肿;因此,我们建议对大于5厘米且有生长倾向的病变进行活检/切除,以便进行适当治疗。

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