Pneumococcal disease and asplenia: the importance of vaccination.

Pneumococcal disease is an important cause of morbidity and mortality, particularly in certain patient groups including those who have been splenectomised or have no functioning spleen. Recent deaths in two asplenic patients from pneumococcal disease should remind doctors of the importance of vaccination in asplenic individuals. The current guidelines for vaccination in such patients are highlighted and discussed. The need for a national asplenic register is also suggested.