染料厂废水浓缩物中的诱变活性。

Mutagenic activity in wastewater concentrates from dye plants.

作者信息

Fracasso M E, Leone R, Brunello F, Monastra C, Tezza F, Storti P V

机构信息

Institute of Pharmacology, Faculty of Medicine, University of Verona, Italy.

出版信息

Mutat Res. 1992 Dec;298(2):91-5. doi: 10.1016/0165-1218(92)90033-v.

DOI:10.1016/0165-1218(92)90033-v

PMID:1282216

Abstract

Wastewater concentrates from the wastewater treatment systems of three dye plants were tested for mutagenic activity in Salmonella typhimurium TA98 and Escherichia coli WP2uvrA using a fluctuation assay. Concentrates were prepared by passing samples of wastewater (5-6 or 30 litres) through two porous resins (XAD-2 and XAD-7) in series. S. typhimurium in the presence of microsomal activation proved to be the more sensitive marker of mutagenicity. Mutagenic responses were observed in concentrates from all three plants tested. The results show that mutagenic activity was particularly high in the incoming waters and increased after active, biological treatment. Physico-chemical treatment may be effective in decreasing mutagenic activity, but only if appropriately used.

摘要

采用波动试验，对三家染料厂废水处理系统的废水浓缩物进行了鼠伤寒沙门氏菌TA98和大肠杆菌WP2uvrA的致突变活性测试。通过使废水样本（5 - 6升或30升）依次通过两种多孔树脂（XAD - 2和XAD - 7）来制备浓缩物。在微粒体激活存在的情况下，鼠伤寒沙门氏菌被证明是更敏感的致突变性标志物。在所测试的所有三家工厂的浓缩物中均观察到致突变反应。结果表明，进水的致突变活性特别高，并且在活性生物处理后有所增加。物理化学处理可能对降低致突变活性有效，但前提是要合理使用。